This product is a 65.7 kDa recombinant human Complement Component C5a R1 protein with a GST-tag at N-terminal expressed in the Wheat Germ (in vitro). It is available for WB, ELISA, PA, AP.
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| Expressed Host | Wheat Germ (in vitro) |
| Specie Reactivity | Human |
| Target | C5aR1 |
| Molecule Mass | 65.7 kDa |
| Purity | >80% by SDS-PAGE and Coomassie Blue staining |
| Formulation | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH 8.0 |
| Applications | WB; ELISA; PA; AP |
| Product Form | Liquid |
| Storage | Store at -20/-80°C. Aliquot to avoid repeated freezing and thawing. |
| Introduction | C5a anaphylatoxin chemotactic receptor 1 is the receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production. |
| Alternative Names | C5a anaphylatoxin chemotactic receptor; C5A; C5aR; C5a-R; C5AR1; C5ARC5a anaphylatoxin receptor; C5R1C5a ligand; CD88 antigen; CD88; complement component 5 receptor 1 (C5a ligand); complement component 5 receptor 1; complement component 5a receptor 1; Complement Component C5a R1; Complement Component C5aR1 |
| Gene ID | 728 |
| UniProt ID | P21730 |