Recombinant Human Complement Factor B Protein-His tag-CTP-106(Cat#: CTP-106)
This product is a 59.4 kDa recombinant human Complement Factor B protein with a N-Terminal His-tag expressed in the E. coli.
Summary
Related Products & Services
Specifications
| Expressed Host |
E. Coli |
| Specie Reactivity |
Human |
| Target |
Factor B |
| Molecule Mass |
59.4 kDa |
| Purity |
>85% by SDS-PAGE |
| Formulation |
20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol |
| Product Form |
Liquid |
| Storage |
Store at -20/-80°C. Aliquot to avoid repeated freezing and thawing. |
Protein Information
| Introduction |
Complement factor B is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes. It also involves in cleavage of Arg-|-Ser bond in complement component C3 alpha-chain to yield C3a and C3b, and Arg-|-Xaa bond in complement component C5 alpha-chain to yield C5a and C5b. |
| Alternative Names |
BF; B-factor, properdin; BFAHUS4; BFD; C3 proaccelerator; C3 proactivator; C3/C5 convertase; CFAB; CFB; Complement Factor B; EC 3.4.21; EC 3.4.21.47; FB; FBI12; GBG; GBGCFAB; Glycine-rich beta; glycine-rich beta-glycoprotein; H2-Bf; PBF2; Properdin factor B |
| Gene ID |
629 |
| UniProt ID |
P00751 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
