Recombinant Human Ficolin 1 Protein-C-terminal His Tag(Cat#: CTP-419)

Name: Recombinant Human Ficolin 1 Protein-C-terminal His Tag
SKU: CTP-419
Rating: 5 (1 reviews)

This product is a 33.6 kDa recombinant human Ficolin 1 protein with a C-terminal His Tag tag expressed in the HEK293 Cells. It is availible for WB, ELISA.

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Specifications

Expressed Host	HEK293 Cells
Specie Reactivity	Human
Target	Ficolin-1
Molecule Mass	33.6 kDa
Purity	>95 % determined by SDS-PAGE
Endotoxin	<1.0EU per 1µg (determined by the LAL method)
Formulation	PBS, pH 7.4, and 5 % - 8 % trehalose, mannitol and 0.01% Tween80
Applications	WB; ELISA
Product Form	Lyophilized
Storage	Store at -20°C/-80°C. Avoid freeze-thaw cycles.

Protein Information

Introduction	Extracellular lectin functioning as a pattern-recognition receptor in innate immunity. Binds the sugar moieties of pathogen-associated molecular patterns (PAMPs) displayed on microbes and activates the lectin pathway of the complement system. May also activate monocytes through a G protein-coupled receptor, FFAR2, inducing the secretion of interleukin-8/IL-8. Binds preferentially to 9-O-acetylated 2-6-linked sialic acid derivatives and to various glycans containing sialic acid engaged in a 2-3 linkage.
Alternative Names	Ficolin 1; FCNM ; Ficolin-Alpha; Ficolin-1; M-Ficolin; Ficolin-A; Ficolin (Collagen/Fibrinogen Domain Containing) 1; FCN1
Gene ID	2219
UniProt ID	O00602

For Research Use Only. Not for Diagnostic or Therapeutic Applications.