Recombinant Human Ficolin 1 Protein-C-terminal His Tag(Cat#: CTP-419)
This product is a 33.6 kDa recombinant human Ficolin 1 protein with a C-terminal His Tag tag expressed in the HEK293 Cells. It is availible for WB, ELISA.
Summary
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Specifications
| Expressed Host |
HEK293 Cells |
| Specie Reactivity |
Human |
| Target |
Ficolin-1 |
| Molecule Mass |
33.6 kDa |
| Purity |
>95 % determined by SDS-PAGE |
| Endotoxin |
<1.0EU per 1µg (determined by the LAL method) |
| Formulation |
PBS, pH 7.4, and 5 % - 8 % trehalose, mannitol and 0.01% Tween80 |
| Applications |
WB; ELISA |
| Product Form |
Lyophilized |
| Storage |
Store at -20°C/-80°C. Avoid freeze-thaw cycles. |
Protein Information
| Introduction |
Extracellular lectin functioning as a pattern-recognition receptor in innate immunity. Binds the sugar moieties of pathogen-associated molecular patterns (PAMPs) displayed on microbes and activates the lectin pathway of the complement system. May also activate monocytes through a G protein-coupled receptor, FFAR2, inducing the secretion of interleukin-8/IL-8. Binds preferentially to 9-O-acetylated 2-6-linked sialic acid derivatives and to various glycans containing sialic acid engaged in a 2-3 linkage. |
| Alternative Names |
Ficolin 1; FCNM ; Ficolin-Alpha; Ficolin-1; M-Ficolin; Ficolin-A; Ficolin (Collagen/Fibrinogen Domain Containing) 1; FCN1 |
| Gene ID |
2219 |
| UniProt ID |
O00602 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
