Recombinant Human MASP-1 Protein-N-terminal His and T7 Tag(Cat#: CTP-410)
This product is a 52.58kDa recombinant human MASP-1 protein with a N-terminal His and T7 Tag tag expressed in the E.coli. It is availible for Positive Control, Immunogen, WB.
Summary
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Specifications
| Expressed Host |
E.coli |
| Specie Reactivity |
Human |
| Target |
MASP1 |
| Molecule Mass |
52.58kDa |
| Purity |
>95 % determined by SDS-PAGE |
| Endotoxin |
<1.0EU per 1µg (determined by the LAL method) |
| Formulation |
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300 |
| Applications |
Positive Control; Immunogen; WB |
| Product Form |
Lyophilized |
| Storage |
Store at -20°C/-80°C. Avoid freeze-thaw cycles. |
Protein Information
| Introduction |
Functions in the lectin pathway of complement, which performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them. The lectin pathway is triggered upon binding of mannan-binding lectin (MBL) and ficolins to sugar moieties which leads to activation of the associated proteases MASP1 and MASP2. Functions as an endopeptidase and may activate MASP2 or C2 or directly activate C3 the key component of complement reaction. Isoform 2 may have an inhibitory effect on the activation of the lectin pathway of complement or may cleave IGFBP5. Also plays a role in development. |
| Alternative Names |
Mannan Binding Lectin Serine Peptidase 1; Complement-Activating Component Of Ra-Reactive Factor ; Mannose-Binding Lectin-Associated Serine Protease 1; C4/C2 Activating Component Of Ra-Reactive Factor ; Mannan-Binding Lectin Serine Protease 1; Ra-Reactive Factor Serine Protease P100; Complement Factor MASP-3; Serine Protease 5; CRARF1; CRARF; PRSS5; MASP; RaRF; MASP-1; MASP1; 3MC1; MAP1 |
| Gene ID |
5648 |
| UniProt ID |
P48740 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
