This product is a recombinant human MBL2 protein with a N-terminal hexahistidine tag expressed in the Mammalian cell (HEK293EBNA1).
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
| Expressed Host | Mammalian Cells (HEK293EBNA1) |
| Specie Reactivity | Human |
| Target | MBL2 |
| Purity | >85% NuPAGE Stained with Coomassie Blue |
| Formulation | PBS without preservative |
| Product Form | Liquid |
| Storage | Store at -20/-80°C. Aliquot to avoid repeated freezing and thawing. |
| Introduction | Mannose-binding protein C is a calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA. |
| Alternative Names | Mannose Binding Lectin 2; Mannose-Binding Lectin (Protein C) 2, Soluble (Opsonic Defect); Mannose-Binding Protein C; Collectin-1; COLEC1; MBP-C; MBP1; MBL; Mannose-Binding Lectin 2, Soluble (Opsonic Defect); Mannose-Binding Lectin (Protein C) 2, Soluble; Mannan-Binding Protein; Mannose-Binding Lectin; HSMBPC; MBL2D; MBPD; MBP |
| Gene ID | 10747 |
| UniProt ID | P11226 |