Recombinant Mouse Adiponectin Protein-Flag tag(Cat#: CTP-235)
This product is a 35 kDa recombinant mouse Adiponectin protein with a Flag tag and a linker peptide (8 aa) at the N-terminus expressed in the HEK 293 cells.
Summary
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Specifications
Expressed Host |
HEK293T Cells |
Specie Reactivity |
Mouse |
Target |
Adiponectin |
Molecule Mass |
~35 kDa (SDS-PAGE) |
Purity |
≥90% as determined by SDS-PAGE |
Endotoxin |
<1.0EU per 1µg (determined by the LAL method) |
Formulation |
PBS |
Product Form |
Lyophilized |
Storage |
Store at 2 to 8°C after reconstitution for short term (1-2 weeks). For long term storage, aliquot and store at -20 or -80°C. Avoid repeated freezing and thawing cycles. |
Protein Information
Introduction |
Adiponectin is an important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW. |
Alternative Names |
Adipocyte complement related protein of 30kDa, ACRP30, AdipoQ, apM1, GBP28 |
Gene ID |
11450 |
UniProt ID |
Q60994 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.