Recombinant Mouse Adiponectin Protein-Flag tag(Cat#: CTP-235)

This product is a 35 kDa recombinant mouse Adiponectin protein with a Flag tag and a linker peptide (8 aa) at the N-terminus expressed in the HEK 293 cells.

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Specifications
Expressed Host HEK293T Cells
Specie Reactivity Mouse
Target Adiponectin
Molecule Mass ~35 kDa (SDS-PAGE)
Purity ≥90% as determined by SDS-PAGE
Endotoxin <1.0EU per 1µg (determined by the LAL method)
Formulation PBS
Product Form Lyophilized
Storage Store at 2 to 8°C after reconstitution for short term (1-2 weeks). For long term storage, aliquot and store at -20 or -80°C. Avoid repeated freezing and thawing cycles.
Protein Information
Introduction Adiponectin is an important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.
Alternative Names Adipocyte complement related protein of 30kDa, ACRP30, AdipoQ, apM1, GBP28
Gene ID 11450
UniProt ID Q60994
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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