This product is a recombinant mouse C5aR1 protein with a rho-1D4 tag tag expressed in the Insect Cells. It is availible for Crys, ELISA, WB.
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| Expressed Host | Insect Cells |
| Specie Reactivity | Mouse |
| Target | C5aR1 |
| Purity | >95 % determined by SDS-PAGE |
| Endotoxin | <1.0EU per 1µg (determined by the LAL method) |
| Formulation | 100 mM NaCL, 20 mM Hepes, 10% glycerol |
| Applications | ELISA; WB |
| Product Form | Liquid |
| Storage | Store at -20°C/-80°C. Avoid freeze-thaw cycles. |
| Introduction | Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production. |
| Alternative Names | Complement C5a Receptor 1; C5AR; C5a Anaphylatoxin Chemotactic Receptor 1; Complement Component 5a Receptor 1; C5a-R; C5R1; CD88; Complement Component 5 Receptor 1 (C5a Ligand); C5a Anaphylatoxin Chemotactic Receptor 4; Complement Component 5 Receptor 1; C5a Anaphylatoxin Receptor; CD88 Antigen; C5AR1; C5aR |
| Gene ID | 12273 |
| UniProt ID | P30993 |