Recombinant Mouse Collectin-11 Protein-N-terminal 10XHis tag and C-terminal Myc tag(Cat#: CTP-447)
This product is a recombinant mouse Collectin-11 protein with a N-terminal 10XHis tag and C-terminal Myc tag tag expressed in the E.coli/Mammalian cell/Baculovirus. It is availible for WB, ELISA.
Summary
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Specifications
| Expressed Host |
E.coli/Mammalian cell/Baculovirus |
| Specie Reactivity |
Mouse |
| Target |
Collectin-11 |
| Purity |
>85 % determined by SDS-PAGE |
| Endotoxin |
<1.0EU per 1µg (determined by the LAL method) |
| Formulation |
Tris-base, 50% glycerol |
| Applications |
WB; ELISA |
| Product Form |
Liquid |
| Storage |
Store at -20°C/-80°C. Avoid freeze-thaw cycles. |
Protein Information
| Introduction |
Collectin-11 (CL-11) is a lectin that plays a role in innate immunity, apoptosis and embryogenesis. Calcium-dependent lectin that binds self and non-self glycoproteins presenting high mannose oligosaccharides with at least one terminal alpha-1,2-linked mannose epitope. Primarily recognizes the terminal disaccharide of the glycan. Also recognizes a subset of fucosylated glycans and lipopolysaccharides. Plays a role in innate immunity through its ability to bind non-self sugars presented by microorganisms and to activate the complement through the recruitment of MAPS1. Also plays a role in apoptosis through its ability to bind in a calcium-independent manner the DNA present at the surface of apoptotic cells and to activate the complement in response to this binding. Finally, plays a role in development, probably serving as a guidance cue during the migration of neural crest cells and other cell types during embryogenesis. |
| Alternative Names |
Collectin Subfamily Member 11; Collectin Kidney Protein 1; Collectin K1; Collectin-11; CL-K1; Collectin Sub-Family Member 11; CL-K1-Iia; CL-K1-Iib; CL-K1-II; COLEC11; 3MC2; CLK1 |
| Gene ID |
71693 |
| UniProt ID |
Q3SXB8 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
