This product is a 22.5 kDa recombinant mouse Complement Component C8G protein with a N-terminal tag or C-terminal tag expressed in the E. Coli or Yeast or Baculovirus or Mammalian Cell.
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| Expressed Host | E. Coli or Yeast or Baculovirus or Mammalian Cell |
| Specie Reactivity | Mouse |
| Target | C8G |
| Molecule Mass | 22.5 kDa |
| Purity | >85% (SDS-PAGE) (lot specific) |
| Endotoxin | <1.0EU per 1µg (determined by the LAL method) |
| Formulation | Tris-based buffer, 50% glycerol |
| Product Form | Liquid containing glycerol |
| Storage | Store at -20/-80°C. Aliquot to avoid repeated freezing and thawing. |
| Introduction | C8 is a constituent of the membrane attack complex. C8 binds to the C5B-7 complex, forming the C5B-8 complex. C5-B8 binds C9 and acts as a catalyst in the polymerization of C9. The gamma subunit seems to be able to bind retinol. |
| Alternative Names | Complement component C8 gamma chain; C8g |
| Gene ID | 69379 |
| UniProt ID | Q8VCG4 |