Recombinant Mouse Complement Factor B Protein-N-terminal His Tag-CTP-299(Cat#: CTP-299)
This product is a recombinant mouse Factor B protein with a N-terminal His Tag tag expressed in the E.coli. It is availible for WB, ELISA.
Summary
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Specifications
| Expressed Host |
E.coli |
| Specie Reactivity |
Mouse |
| Target |
Factor B |
| Purity |
>90 % determined by SDS-PAGE |
| Endotoxin |
<1.0EU per 1µg (determined by the LAL method) |
| Formulation |
20 mM Tris-HCl based buffer, pH 8.0 |
| Applications |
WB; ELISA |
| Product Form |
Lyophilized |
| Storage |
Store at -20°C/-80°C. Avoid freeze-thaw cycles. |
Protein Information
| Introduction |
Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes. |
| Alternative Names |
Complement Factor B; B-Factor, Properdin; Properdin Factor B; Glycine-Rich Beta-Glycoprotein; Glycine-Rich Beta Glycoprotein; C3 Proaccelerator; C3 Proactivator; CFB; FB |
| Gene ID |
14962 |
| UniProt ID |
P04186 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
