This product is a recombinant mouse Factor B protein with a N-terminal His Tag tag expressed in the E.coli. It is availible for WB, ELISA.
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| Expressed Host | E.coli |
| Specie Reactivity | Mouse |
| Target | Factor B |
| Purity | >90 % determined by SDS-PAGE |
| Endotoxin | <1.0EU per 1µg (determined by the LAL method) |
| Formulation | 20 mM Tris-HCl based buffer, pH 8.0 |
| Applications | WB; ELISA |
| Product Form | Lyophilized |
| Storage | Store at -20°C/-80°C. Avoid freeze-thaw cycles. |
| Introduction | Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes. |
| Alternative Names | Complement Factor B; B-Factor, Properdin; Properdin Factor B; Glycine-Rich Beta-Glycoprotein; Glycine-Rich Beta Glycoprotein; C3 Proaccelerator; C3 Proactivator; CFB; FB |
| Gene ID | 14962 |
| UniProt ID | P04186 |