Recombinant Pig CD59 Protein-N-terminal His Tag(Cat#: CTP-347)

This product is a 12.3kDa recombinant Pig CD59 protein with a N-terminal His Tag tag expressed in the E.coli. It is availible for Positive Control, Immunogen, WB.

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Specifications
Expressed Host E.coli
Specie Reactivity Pig
Target CD59
Molecule Mass 12.3kDa
Purity >95 % determined by SDS-PAGE
Endotoxin <1.0EU per 1µg (determined by the LAL method)
Formulation PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300
Applications Positive Control; Immunogen; WB
Product Form Lyophilized
Storage Store at -20°C/-80°C. Avoid freeze-thaw cycles.
Protein Information
Introduction Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.
The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes.
Alternative Names CD59 Molecule; CD59 Molecule, Complement Regulatory Protein; Membrane Attack Complex Inhibition Factor; 20 KDa Homologous Restriction Factor; Membrane Inhibitor Of Reactive Lysis; CD59 Glycoprotein; MEM43 Antigen; MAC-IP; CD59; MAC-Inhibitory Protein; CD59 Antigen, Complement Regulatory Protein; MAC-Inhibitory Protein; Protectin
Gene ID 397347
UniProt ID O62680
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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