Recombinant Pig Complement C3 Protein-N-terminal His Tag(Cat#: CTP-518)

Name: Recombinant Pig Complement C3 Protein-N-terminal His Tag
SKU: CTP-518

This product is a recombinant Pig C3 protein with a N-terminal His Tag tag expressed in the E.coli. It is availible for WB, ELISA, IP.

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Specifications

Expressed Host	E.coli
Specie Reactivity	Pig
Target	C3
Purity	>95 % determined by SDS-PAGE
Endotoxin	<1.0EU per 1µg (determined by the LAL method)
Formulation	PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300
Applications	WB; ELISA; IP
Product Form	Lyophilized
Storage	Store at -20°C/-80°C. Avoid freeze-thaw cycles.

Protein Information

Introduction	C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. In chronic inflammation, acts as a chemoattractant for neutrophils (By similarity). It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. [C3-beta-c]: Acts as a chemoattractant for neutrophils in chronic inflammation. [Acylation stimulating protein]: adipogenic hormone that stimulates triglyceride (TG) synthesis and glucose transport in adipocytes, regulating fat storage and playing a role in postprandial TG clearance. Appears to stimulate TG synthesis via activation of the PLC, MAPK and AKT signaling pathways. Ligand for C5AR2. Promotes the phosphorylation, ARRB2-mediated internalization and recycling of C5AR2.
Alternative Names	Complement C3; Complement Component 3; Complement Component C3; C3
Gene ID	397072
UniProt ID	P01025

Customer Review

Highly recommended for researchers needing high-quality complement proteins

Excellent

The purity and concentration of the protein were as advertised, and it worked seamlessly in our ELISA assays. We observed consistent and reproducible results, which significantly advanced our study on complement activation.

The protein was delivered with detailed specifications, and the His Tag allowed for easy purification using standard protocols

Excellent

Our Western blot results were very promising, showing clear bands with high specificity. The recombinant C3 protein has proven essential for our studies on complement pathways, and we appreciate the reliability of this reagent.

The protein's performance in our experiments has been very reliable

Excellent

The His Tag facilitated efficient purification. The product was well-packaged and arrived on time. We are pleased with its functionality and will continue using it in future experiments.

High quality and performance

Excellent

In Western Blots, we observe clean, distinct bands, indicating high purity. ELISA assays also show excellent signal-to-noise ratios, which is crucial for our quantitative analysis.

Its quality has been consistently reliable

Excellent

The His Tag makes the protein easy to purify, and the resulting product shows excellent performance in WB with clear, specific bands.

For Research Use Only. Not for Diagnostic or Therapeutic Applications.