This product is a 14.8kDa recombinant Rabbit CD59 protein with a N-terminal His Tag tag expressed in the E.coli. It is availible for Positive Control, Immunogen, WB.
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| Expressed Host | E.coli |
| Specie Reactivity | Rabbit |
| Target | CD59 |
| Molecule Mass | 14.8kDa |
| Purity | >97 % determined by SDS-PAGE |
| Endotoxin | <1.0EU per 1µg (determined by the LAL method) |
| Formulation | PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300 |
| Applications | Positive Control; Immunogen; WB |
| Product Form | Lyophilized |
| Storage | Store at -20°C/-80°C. Avoid freeze-thaw cycles. |
| Introduction | Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes. |
| Alternative Names | CD59 Molecule; CD59 Molecule, Complement Regulatory Protein; Membrane Attack Complex Inhibition Factor; 20 KDa Homologous Restriction Factor; Membrane Inhibitor Of Reactive Lysis; CD59 Glycoprotein; MEM43 Antigen; MAC-IP; CD59; MAC-Inhibitory Protein; CD59 Antigen, Complement Regulatory Protein; MAC-Inhibitory Protein; Protectin |
| Gene ID | 9459 |
| UniProt ID | O77541 |