Recombinant Rat Adiponectin Protein-Flag tag(Cat#: CTP-236)
This product is a 25.7 kDa recombinant rat Adiponectin protein with a C-Terminal Flag- tag (8 AA residue) expressed in the HEK 293 cells.
Summary
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Specifications
Expressed Host |
HEK293T Cells |
Specie Reactivity |
Rat |
Target |
Adiponectin |
Molecule Mass |
25.7 kDa |
Purity |
>90.0% as determined by densitometric image analysis |
Formulation |
20 mM Tris buffer, 50 mM NaCl, pH 7.5 |
Product Form |
Lyophilized |
Storage |
Store at 2 to 8°C after reconstitution for short term (1-2 weeks). For long term storage, aliquot and store at -20 or -80°C. Avoid repeated freezing and thawing cycles. |
Protein Information
Introduction |
Adiponectin is an important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW. |
Alternative Names |
Adipocyte C1q and collagen domain-containing protein, Adipocyte complement-related 30kDa protein, Adipose most abundant gene transcript 1 protein, gelatin-binding protein, Acrp30, AdipoQ, GBP-28, APM-1, ACDC. |
Gene ID |
246253 |
UniProt ID |
Q8K3R4 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.