This product is a 32 kDa recombinant rat Complement Component C2 protein with a N-terminal His Tag expressed in the E. Coli. It is available for WB, ELISA, IP.
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| Expressed Host | E. Coli |
| Specie Reactivity | Rat |
| Target | C2 |
| Molecule Mass | 32 kDa |
| Purity | >95% as determined by SDS-PAGE |
| Endotoxin | <1.0EU per 1µg (determined by the LAL method) |
| Formulation | 100 mM NaHCO3, 500 mM NaCl, pH 8.3, containing 1 mM EDTA, 1 mM DTT, 0.01% SKL, 5% Trehalose and Proclin 300 |
| Applications | WB; ELISA; IP |
| Product Form | Lyophilized |
| Storage | Store at 2 to 8°C after reconstitution for short term (1-2 weeks). For long term storage, aliquot and store at -20 or -80°C. Avoid repeated freezing and thawing cycles. |
| Introduction | Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase. C2 is a major histocompatibility complex class-III protein. Selective cleavage of Arg-|-Ser bond in complement component C3 alpha-chain to form C3a and C3b, and Arg-|-Xaa bond in complement component C5 alpha-chain to form C5a and C5b. |
| Alternative Names | Complement C2; Complement Component 2; C3/C5 Convertase; Complement Component C2; EC 3.4.21.43; ARMD14; CO2 |
| Gene ID | 24231 |
| UniProt ID | Q6MG73 |