This product is a 64kDa recombinant rat Factor B protein with a N-terminal His and MBP Tag tag expressed in the E.coli. It is availible for Positive Control, Immunogen, WB.
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
| Expressed Host | E.coli |
| Specie Reactivity | Rat |
| Target | Factor B |
| Molecule Mass | 64kDa |
| Purity | >95 % determined by SDS-PAGE |
| Endotoxin | <1.0EU per 1µg (determined by the LAL method) |
| Formulation | 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300 |
| Applications | Positive Control; Immunogen; WB |
| Product Form | Lyophilized |
| Storage | Store at -20°C/-80°C. Avoid freeze-thaw cycles. |
| Introduction | Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes. |
| Alternative Names | Complement Factor B; B-Factor, Properdin; Properdin Factor B; Glycine-Rich Beta-Glycoprotein; Glycine-Rich Beta Glycoprotein; C3 Proaccelerator; C3 Proactivator; CFB; FB |
| Gene ID | 294257 |
| UniProt ID | G3V615 |