Recombinant Rat Ficolin 1 Protein-N-terminal 6XHis tag(Cat#: CTP-426)

Name: Recombinant Rat Ficolin 1 Protein-N-terminal 6XHis tag
SKU: CTP-426
Rating: 5 (1 reviews)

This product is a recombinant rat Ficolin 1 protein with a N-terminal 6XHis tag tag expressed in the Yeast. It is availible for WB, ELISA.

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Specifications

Expressed Host	Yeast
Specie Reactivity	Rat
Target	Ficolin-1
Purity	>85 % determined by SDS-PAGE
Endotoxin	<1.0EU per 1µg (determined by the LAL method)
Formulation	Tris-base, 50% glycerol
Applications	WB; ELISA
Product Form	Liquid
Storage	Store at -20°C/-80°C. Avoid freeze-thaw cycles.

Protein Information

Introduction	Extracellular lectin functioning as a pattern-recognition receptor in innate immunity. Binds the sugar moieties of pathogen-associated molecular patterns (PAMPs) displayed on microbes and activates the lectin pathway of the complement system. May also activate monocytes through a G protein-coupled receptor, FFAR2, inducing the secretion of interleukin-8/IL-8. Binds preferentially to 9-O-acetylated 2-6-linked sialic acid derivatives and to various glycans containing sialic acid engaged in a 2-3 linkage.
Alternative Names	Ficolin 1; FCNM ; Ficolin-Alpha; Ficolin-1; M-Ficolin; Ficolin-A; Ficolin (Collagen/Fibrinogen Domain Containing) 1; FCN1
Gene ID	83517
UniProt ID	Q9WTS8

For Research Use Only. Not for Diagnostic or Therapeutic Applications.