SB290157 (Trifluoroacetate)(Cat#: CTI-001)
This product is a potent C3a receptor antagonist, it selectively inhibits C3aR with the IC50 of 200 nM.
Summary
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Specifications
| CAS No. |
1140525-25-2 |
| Formula |
C₂₄H₂₉F₃N₄O₆ |
| Molecular Weight |
526.51 |
| SMILES |
N=C(N)NCCC[C@@H](C(O)=O)NC(COCC(C1=CC=CC=C1)C2=CC=CC=C2)=O.OC(C(F)(F)F)=O |
| IC50 |
IC50: 200 Nm |
| Purity |
95% |
| Solubility |
DMSO: 125 mg/mL (Need ultrasonic) |
| Storage |
Store at -4°C for short term; at -20 °C for long-term storage. |
| Target |
C3aR |
| Introduction |
The anaphylatoxin C3a, a potent chemotactic peptide and inflammatory mediator, binds to and activates a G-protein-coupled receptor. Molecular cloning of the C3aR has facilitated the identification of the non-peptide C3aR antagonists. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
