W-54011(Cat#: CTI-005)

Name: W-54011
SKU: CTI-005
Rating: 5 (1 reviews)

This product is a potent C5a receptor antagonist, it inhibits C5aR with the Ki value of 2.2 nM.

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Specifications

CAS No.	405098-33-1
Formula	C₃₀H₃₇ClN₂O₂
Molecular Weight	493.08
SMILES	O=C(C1CCCC2=C1C=C(OC)C=C2)N(CC3=CC=C(N(C)C)C=C3)C4=CC=C(C(C)C)C=C4.[H]Cl
IC50	IC50: 2.2 nM
Purity	98%
Solubility	DMSO :> 28 mg/mL (56.79 mM)
Storage	Store at -4°C for short term; at -20 °C for long-term storage.
Target	C5aR
Introduction	The C5a receptor also known as C5AR1 or CD88 (Cluster of Differentiation 88), is a G protein-coupled receptor for C5a. It functions as a complement receptor. C5a receptor modulates inflammatory responses, obesity, development and cancers

For Research Use Only. Not for Diagnostic or Therapeutic Applications.