Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
Highlights| Protein Name | Cysteinyl leukotriene receptor 1 |
| Gene Name | CYSLTR1 |
| Uniprot | Q9Y271 (Human); Q99JA4 (Mouse) |
| Synonym | CYSLT1; CYSLTR; CYSLT1R; HMTMF81; G-protein coupled receptor HG55; LTD4 receptor; cysteinyl leukotriene D4 receptor |
| Background | CYSLTR1, encode by CYSLTR1 gene, belongs to the G protein-coupled receptor family which has seven transmembrane domains. It is widely expressed in many human tissues, such as urinary bladder, spleen, lymph node, gallbladder, esophagus, appendix and so on. Recently, most studies have shown that CYSLTR1 plays an essential role in multiple metabolic activities, involved in the mediation of inflammatory reaction and tumors progression. |
Creative Biolabs offers comprehensive range of membrane protein products empowers your unique research needs.
| CAT# | Product Name | Expression System | Protein Length | Solubilizing Agents |
| S01YF-1023-KX289 | NativeExtract™ Human CYSLTR1 Membrane Protein (Full length, Super Nanodisc) | HEK293 cells | Full length | Native Nanodisc |
| S01YF-0622-KX141 | MemDX™ Recombinant Human CYSLTR1 Membrane Protein in Virus-Like Particles (MP-VLPs) | HEK293 cells | Full length | VLPs |
| MPX0892K | MemDX™ Membrane Protein Human CYSLTR1 Expressed in vitro E.coli expression system, Full Length | E.coli cell-free | Full length | Detergent |
| MP0292X | MemDX™ Membrane Protein Human CYSLTR1 (Cysteinyl leukotriene receptor 1) for Antibody Discovery | Wheat germ cell-free | Full length | N/A |
| Please for more products or customization | ||||
O***r: Creative Biolabs' technical support team is knowledgeable and helpful, ensuring that I had a smooth experience from purchase to delivery.
26/Feb/2023
L**m: I highly recommend Creative Biolabs for anyone in need of high-quality research materials. Their dedication to quality and customer satisfaction is evident in every aspect of their service.
12/Oct/2023
We provide tailored solutions to meet your specific requirements. Please for more services.
qPCR for Gene Expression
Creative Biolabs offers gene expression services. Quantitative polymerase chain reaction (qPCR) represents a fundamental and exceptionally versatile technique within molecular biology. This methodology is routinely leveraged for the precise assessment of gene expression levels, specifically concerning the transcript abundance of entities like CYSLTR1, across an extensive array of diverse cellular phenotypes and heterogeneous tissue configurations.
DNA Methylation Analysis
Creative Biolabs offers DNA methylation analysis services. Epigenetic modifications, notably DNA methylation, are acknowledged as pivotal regulatory mechanisms that exert significant influence upon gene transcriptional activity. This dynamic interplay perhaps extends to, and consequently modulates, the expression profile of CYSLTR1 within various biological systems.
Gene Therapy Vectors
Creative Biolabs offers gene therapy vectors development services. Molecular intervention strategies frequently leverage either recombinant viral or synthetic non-viral vector systems. These advanced delivery vehicles are engineered to mediate the intracellular transfer of nucleic acid constructs, which may encompass either exogenous gene sequences or RNA molecules specifically designed to modulate the expression of CYSLTR1. In a tangible illustration, adenoviral vectors can be judiciously engineered to express short hairpin RNAs (shRNAs) that are highly specific for CYSLTR1 transcripts. The introduction of such constructs into target cellular populations can consequently lead to the targeted post-transcriptional gene silencing of CYSLTR1.
Creative Biolabs offers comprehensive and innovative services to drive the development of CYSLTR1 cell therapy. Please for more services.
Animal Models
Creative Biolabs offers animal models development services. Genetically engineered murine models, particularly those incorporating targeted gene deletion, constitute invaluable experimental platforms. These sophisticated biological systems enable the meticulous investigation into the precise mechanistic involvement of specific molecular entities, such as CYSLTR1, within the intricate processes of disease pathogenesis and the nuanced spectrum of therapeutic responsiveness.
Xenograft Models
Creative Biolabs offers xenograft models development services. Heterologous xenograft models are established by subcutaneously or orthotopically engrafting human neoplastic cellular lineages into immunocompromised murine hosts. These systems serve as sophisticated platforms for the comprehensive investigation into the precise impact of pharmacological agents, specifically antagonists targeting the CYSLTR1, upon fundamental aspects of tumorigenic progression and their capacity to induce subtle yet significant immunomodulatory responses within the tumor microenvironment.
PD-L1 Expression
Creative Biolabs offers PD-L1 expression analysis services. Signaling pathways mediated by CYSLTR1 actively participate in the regulation of programmed death-ligand 1 (PD-L1) expression on the surface of malignant cellular populations. This intricate interplay between CYSLTR1 activity and PD-L1 abundance represents a potentially significant mechanism within the tumor microenvironment. Either the genetic ablation or the pharmacological inhibition of CYSLTR1 function, through the administration of targeted antagonists, has been demonstrated to attenuate PD-L1 expression. This observed reduction in PD-L1 levels on tumor cells consequently suggests a promising avenue.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
