Creative Biolabs offers a number of high-quality biotin labeling services for our global customers for biomedical research use. Based on a wealth of experience and advanced technology, we are capable of designing and manufacturing both custom and customized antibody conjugation project in close co-operation with our clients. In particular, our skilled experts enable us to offer quick and optimized conjugate results with excellent quality.

What is Biotin Labeling?

Biotin, also known as vitamin B7, is a small biologically active molecule that acts as a co-enzyme in living cells. It can be coupled to oligonucleotides at the terminal and internal position at multiple sites. Biotin labeling (also called biotinylation) is the process of covalently attaching biotin to a protein, nucleic acid or other molecule, which has been widely used in numerous detection systems especially when the target of interest is expressed at low levels and cannot be detected by labeled antibodies alone. Generally, biotinylation is rapid, specific and is unlikely to perturb the natural function of the molecule due to the small size of biotin. Most importantly, many biotin molecules can be conjugated to an antibody with extremely high affinity, fast-on-rate, and high specificity, which does not appear in the conjugation with streptavidin and avidin. Through this amplification step, proteins which are expressed at low levels are more likely to be detected.

Biotin Labeling of Proximal Proteins in Live Cells. Fig.1 Biotin Labeling of Proximal Proteins in Live Cells. (Lönn., 2017)

Biotin Labeling Services Provided by Creative Biolabs

Having providing protein biotin labeling service for many years, Creative Biolabs is capable of offering a full range of custom biotinylation services for both academic and industrial customers. With experienced scientists, we can label any protein with biotin as our clients required. Our advanced protein biotinylation platform enables us to provide simple and efficient biotin labeling without altering the bioactivity of target proteins. What’s more, we have developed multiple biotin labeling approaches to satisfy worldwide customer’s requirements.

Our Advantages

  • Rich experience: Years of experience and more than 100 biotins labeled proteins have been delivered.
  • Mature technology: Advanced biotinylation platform and mature technology enable us to offer you high-quality biotin labeling service with high sensitivity.
  • Short duration: Fast turnaround time with a relatively low price.

Creative Biolabs is committed to offering high-quality biotin labeling services for worldwide customers. With advanced technology and proficient scientists, we can assure you both biotinylation efficiency and protein activity preservation. Moreover, our biotin labeling service is reproducible and quality guaranteed. For more detailed information, please feel free to contact us and get a quote. We will get in touch with you within 24 hours and design an optimal method for your project.

Reference

  1. Lönn., (2017) "Close Encounters–Probing Proximal Proteins in Live or Fixed Cells." Trends in biochemical sciences 42.7: 504-515.


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