Date: May 10, 2020 Acs Sens

Raising Global Awareness for Rare Diseases on Rare Disease Day

Rare Disease Day takes place worldwide, typically on or near the last day of February each year, to raise awareness among the public and policymakers about rare diseases and their impact on patients’ lives. The power and promise of genomics for the diagnosis of rare diseases are exemplified in many cases. Wider attention and intensify discussion are needed to advance the development of diagnosis and treatment of rare diseases.

Date: May 10, 2020 Acs Sens

Lens-free Diffraction Reconstruction Enables In Vitro Cancer Early Detection

Molecular diagnosis is the main method for detecting cancer-associated gene and tumor marker. Researchers proposed a high-throughput and cost-effective approach based on molecular diagnosis of target tumor marker and a lensfree diffraction imaging platform. This approach achieves high-speed and high-quality reconstruction of huge images. Besides, the cells which are labeled with immune microbeads can be screened using the determined covered pixel sets, which are extracted in different focus reconstruction planes. The detection equipment is cost-effective and easy to operate and popularize. It is expected to be widely used as a diagnostic tool for early detection of cancer. This work was published in ACS Sensors. Key Points: High throughput, Cancer early detection, In vitro diagnosis (IVD)

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