While the Internet age led to the interconnectedness between people at an unprecedented rate, the next revolution will involve the connectedness of objects: integrating electronics, computing, communications, and transducers to create a smart environment through the Internet of Things (IoT). Extending these transformative changes to health care has the potential to exponentially improve lives. As an industry-leading company, Creative Biolabs has strong foundations and mature technologies. We are confident in providing global customers with high-quality IoT-based Microfluidic system development services.

Introduction of IoT for Medical Applications

As we move into the IoT and cloud computing era, the number of sensors deployed that seamlessly integrate themselves into the environment is growing rapidly. This concept is described as a totally interconnected world where devices of every shape and size are manufactured with smart capabilities that allow them to communicate and interact with other devices, exchange data, make autonomous decisions, and perform useful tasks based on preset conditions. Wearable devices and sensors would be ubiquitously employed to continuously monitor health and infrastructure that would subsequently be uploaded to data centers and archived as datasets. These datasets then provide the training necessary for data scientists and physicians to make intelligent predictions based on the behavior of their clients.

Wearables devices for medical applications.Fig.1 Wearables devices for medical applications. (Yetisen, 2018)

Applications of IoT-Based Microfluidic System

Microfluidics is a multidisciplinary field intersecting engineering, nanotechnology, physics, and chemistry with practical applications to design systems in which small volumes of fluids will be handled. There are a variety of sensors and circuits for IoT healthcare applications ranging from cardiovascular sensing (to be integrated with smart-watch applications) to unpowered Microfluidic pressure sensors for glaucoma diagnosis to flexible tactile sensor arrays for smart skin applications.

  • Microfluidic contact lenses

Microfluidic contact lenses have been fabricated by laser ablation and fiber templating. A microlithography method has been developed to create microconcavities and microchannels in contact lenses. The Microfluidic channel diameters ranged from 100 to 150µm and their stability properties were evaluated by flow testing of artificial fluid. Microfluidic contact lenses were also functionalized with fluorophores to demonstrate their optical emission capabilities in the visible spectrum. Microfluidic contact lenses may allow sampling tear fluid for multiplexed sensing in vivo and they may simultaneously deliver drugs to the eye.

  • Microfluidic-based drug delivery system

Microfluidic systems have been developed to deliver drugs to inner ear fluid. A Microfluidic device has been fabricated to infuse and withdraw sub-microliter drug solutions to and from inner ear fluid to achieve a liquid transfer with zero net volume. The drug delivery system consisted of a polymer reciprocating pump and an electromagnetic actuator for application in head-mounted wearables. The mass transport of the drug molecules to the cochlea was achieved through diffusion and mixing. The programmable pump created a reciprocating flow and a reservoir to control the drug concentration in the infused bolus.

Services at Creative Biolabs

Internet of Things based Microfluidic System Development Services

Committed to in vitro diagnostic (IVD) researches for years, Creative Biolabs has step-by-step equipped our technology platform with advanced facilities, novel methods, and excellent scientific staff. As an industry-leading CRO company, we have never stopped making progress and thrown our sight into the IoT-based Microfluidic system development. With strong foundations and rich experience, we are capable of providing high-quality IoT-based Microfluidic system development services.

With excellent industrial capacities, Creative Biolabs is eager to bring our clients reliable services with top-rated customer experiences. If you are interested in IoT-based Microfluidic system development services or other IVD development services, please don't hesitate to contact us for more information.

Reference

  1. Yetisen, A. K.; et al. Wearables in medicine. Adv Mater. 2018, : e1706910.

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