Creative Biolabs is a famous expert in the in vitro diagnostics (IVD) manufacture, including IVD antibody productions and fast kit developments. Currently, we offer lateral-flow immunochromatographic assay (LFIA) based kits developed services to complete disease screening and diagnosis, infection detection and therapeutic monitoring. Our company satisfies application-specific customized services based on client’s diverse needs.
Lateral-flow Immunochromatographic Assay
LFIA, also known as lateral flow immunoassay, lateral flow assay (LFA), lateral flow test (LFT) or lateral flow device (LFD), is a type of solid-phase immunoassay that combines the principles of thin layer chromatography and immune recognition reaction. In this assay, colored particles (colloidal gold, colloidal carbon, colloidal selenium, liposome, latex, quantum dot, and so on) can be selected as labels of antibody to detect the presence of an analyte. Based on the elements of recognition used, LFIA can be categorized into different types as follows.
Fig.1 Classification of lateral flow assays. (Koczula, K.M., 2016)
LIFA is a paper-based system for the detection and quantification of the target analyte in complex mixtures, where the sample is put into a test device, and results showed within few minutes. Compared to the laboratory-oriented instrumental analysis, LFIA is a simple, inexpensive, and fast-response technique useful for medical diagnosis, basic research, home testing, and point of care testing, as well as detecting various agricultural and environmental contaminations.
Advantages of LFIA
As the increasing popularity of this method, there are a number of prominent and unique merits performed in LFIA, including:
LFIA-based Kits Development
LFIA is designed to confirm the presence or absence of the desired analyte, including pathogens and biomarkers in humans or animals, or contaminants in foodstuffs, water supplies, or animal feeds. The most commonly known application of this assay is the pregnancy test. Ease of productions and low development costs of LFIA have led the expansion of its applications to multiple areas in which rapid tests are basically required. LFIA-based tests are widely applied in hospitals, biological and clinical laboratories for the qualitative and quantitative detection of specific antigens, antibodies, and gene amplification products.
In Creative Biolabs, we have developed high-quality LFIA-based kits for IVD. By using our IVD kits, varieties of biological specimens can be tested, involving saliva, sweat, urine, serum, plasma, whole blood, and other fluids. Moreover, further industries in which LFIA-based kits can be served that include quality control, veterinary medicine, product safety of food production, and environmental health and safety. For more detailed information, please feel free to contact us.
Reference
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