Cell Signaling Phospho Antibody Array features 304 high-specificity antibodies targeting key nodes across 16 widely studied cell signaling pathways, optimized for protein phosphorylation profiling using human, mouse, and rat cell and tissue samples. Each kit includes two identical array slides, enabling parallel analysis of two independent samples, such as a control specimen and a treated experimental sample.
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Product Property | |
|---|---|
| Species Reactivity | Human; Mouse; Rat |
| Sample Type | Cell lysate; Tissue lysate |
| Assay Type | Fluorescent Immunoassay |
| Detection Method | Fluorescence Scanning |
| Internal Controls | Beta-actin; GAPDH; Negative controls |
| Principle | Fluorescent immunoassay based on antibody microarray, for quantitative detection of cell signaling pathway phosphorylation levels. |
| Platform | Fluorescent Antibody Microarray |
| Specificity | Human |
| Cross-Reaction | Mouse; Rat |
| Product Content | 2 array slides per package for analyzing two samples (untreated vs. treated) |
| Slide Dimensions | 76 x 25 x 1 mm |
| Application Notes | ELISA based antibody array |
| Core Highlights | 304 antibodies from 16 cell signaling pathways Site-specific phosphorylation profiling and screening Antibodies covalently immobilized on 3D polymer coated glass slide Fluorescent detection |
| Signaling Pathway | Cell Signaling |
| Storage | 2-8°C |
Target Information | |
|---|---|
| Analyte | Cell Signaling Phosphoproteins |
| Targets | PI3K/AKT AKT1, AKT2, BAD, BCL2, CASP9, CCND1, CCNE1, CDK2, CKDN1A, CHUK, CREB1, EGFR1, EIF4E, EIF4EBP1, ERBB2, FOXO3, GSK3B, HSP90AB1, IGF1R, IKBKB, IKBKG, IL4R, IRS1, ITGB3, JAK1, JAK2, KDR, MAP2K1, MDM2, MET, MTOR, MYC, NFKB1, NOS3, NTRK2, PDGFRB, PDK1, PPP2CA, PRKAA1, PTEN, PTK2, RAF1, RELA, RPS6KB1, STK11, SYK, TP53, TSC2, YWHAQ AMPK ACACA, AKT1, AKT1S1, AKT2, CCND1, CREB1, EEF2, EEF2K, EIF4EBP1, FOXO1, FOXO3, IFG1R, IRS1, MAP3K7, MTOR, PDPK1, PPARG, PPP2CA, PRKAA1, RPS6KB1, SREBF1, STK11, TSC2 Apoptosis ACTB, ACTG1, AKT1, AKT2, BAD, BAX, BCL2, BID, CASP3, CASP8, CASP9, CHUK, EIF2S1, FADD, FOS, IKBKB, IKBKG, LMNA, MAP2K1, MAP3K5, MAPK9, NFKB1, NFKB1A, PDPK1, RAF1, RELA, TP53 Autophagy AKT1, AKT1S1, AKT2, BAD, BCL2, BECN1, EIF2S1, IGF1R, IRS1, MAP2K1, MAP3K7, MAPK9, MTOR, PDPK1, PPP2CA, PRKAA1, PTEN, RAF1, RPS6KB1, STK11, TSC2 Cell Cycle ABL1, CCND1, CCNE1, CDC25C, CDK2, CDKNIA, CHEK1, CHEK2, GSK3B, HDAC1, HDAC2, MDM2, MYC, PLK1, RB1, SMAD2, SMAD3, TP53, YWHAQ ErbB ABL1, AKT1, AKT2, BAD, BRAF, CAMK2A, CAMK2B, CAMK2D, CAMK2G, CBL, CDKN1A, CRK, EGFR, EIF4EBP1, ELK1, ERBB2, GAB1, GSK3B, MAP2K1, MAP2K4, MAPK9, MTOR, MYC, PAK1, PLCG1, PTK2, RAF1, RPS6KB1, SHC1, SRC, STAT5A, STAT5B Focal Adhesion ACTB, ACTG1, AKT1, AKT2, BAD, BCL2, BRAF, CCND1, CRK, CTNNB1, EGFR, ELK1, ERBB2, GSK3B, IGF1R, ITGB3, KDR, MAP2K1, MAKP9, MET, PAK1, PDGFRB, PDPK1, PPP1CA, PTEN, PTK2, RAF1, RASGRF1, SHC1, SRC, VASP Insulin ACACA, AKT1, AKT2, BAD, BRAF, CALM1, CBL, CRK, EIF4E, EIF4EBP1, ELK1, FOXO1, GSK3B, IKBKB, IRS1, MAK2K1, MAPK9, MTOR, PDPK1, PPP1CA, PRKAA1, RAF1, RPS6KB1, SHC1, SREBF1, TSC2 , JAK-STAT AKT1, AKT2, BCL2, CCND1, CDKN1A, EGFR, IFNGR1, IL10RA, IL4R, JAK1, JAK2, MTOR, MYC, PDGFRB, PTPN11, RAF1, STAT1, STAT2, STAT3, STAT4, STAT5A, STAT5B, STAT6 MAPK AKT1, AKT2, BRAF, CHUK, CRK, EGFR, ELK1, ERBB2, FOS, HSPB1, IGR1R, IKBKG, KDR, MAP2K1, MAP2K4, MAP3K5, MAP3K7, MAPK14, MAPK9, MAPT, MET, MYC, NFKB1, NTRK2, PAK1, PDFGRB, RAF1, RASGRF1, RELA, RELB, RPS6KA1, RPS6KA2, RPS6KA3, RPS6KA5, SRF, TP53, CASP3 mTOR AKT1, AKT1S1, AKT2, BRAF, CHUK, EIF4E, EIF4EBP1, GSK3B, IFG1R, IKBKB, IRS1, MAP2K1, MTOR, PDPK1, PRKAA1, PTEN, RAF1, RPS6KA1, RPS6KA2, RPS6KA3, RPS6KB1, STK11, TSC2, WNT1 NF-kappa B BCL2, BLNK, CHUK, IKBKB, IKBKG, LCK, LYN, MAP3K7, NFKB1, NFKB1A, PLCG1, RELA, RELB, SYK, ZAP70 p53 BAX, BCL2, BID, CASP8, CASP9, CCND1, CCNE1, CDK2, CDKNIA, CHEK1, CHEK2, MDM2, PTEN, TP53, TP73, TSC2, CASP3, CASP8 Ras ABL1, AKT1, AKT2, BAD, CALM1, CHUK, EGFR, ELK1, GAB1, GAB2, GRIN1, IGF1R, IKBKB, IKBKG, KDR, MAP2K1, MAPK9, MET, NFKB1, PAK1, PDFGRB, PLCG1, PTPN11, RAF1, RASGRF1, RELA, SHC1, ZAP70 TGF-beta MYC, PPP2CA, RPS6KB1, SMAD1, SMAD2, SMAD3, TGFBR1, TGFBR2 VEGF AKT1, AKT2, BAD, CASP9, HSPB1, MAP2K1, MAPK14, NOS3, PLCG1, PTK2, RAF1, SRC, VEGFR2 |
| Target Source | Human; Mouse; Rat |
For Research Use Only.