Anti-Diazepam Binding Inhibitor (DBI) Antibody Pair Set Capture Antibody: Rabbit Polyclonal IgGDetection Antibody: Mouse Monoclonal IgG-Biotin
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Antigen Detail | |
|---|---|
| Target | Diazepam Binding Inhibitor (DBI) |
| Species Reactivity | Human |
Capture Antibody | |
|---|---|
| Capture Clonality | Polyclonal |
| Host Species | Rabbit |
| Isotype | IgG |
| Purification | Affinity Chromatography |
| Buffer | PBS, pH 7.4, containing 0.1% Proclin 300 |
| Application | ELISA |
Detection Antibody | |
|---|---|
| Det-Clonality | Monoclonal |
| Host Species | Mouse |
| Conjugation | Biotin |
| Clone | RD10101 |
| Isotype | IgG |
| Purification | Affinity Chromatography |
| Application | PBS, pH 7.4, containing 0.1% sodium azide |
General Product Property | |
|---|---|
| Product Overview | Anti-Diazepam Binding Inhibitor (DBI) Antibody Pair Set Capture Antibody: Rabbit Polyclonal IgG Detection Antibody: Mouse Monoclonal IgG-Biotin |
| Specificity | The specificity of capture antibody: Specific for Diazepam Binding Inhibitor (DBI) The specificity of detection antibody: Specific for Diazepam Binding Inhibitor (DBI) |
| Application | ELISA |
| Application Notes | Optimal dilutions should be determined experimentally by the user. |
| Form | Liquid |
| Storage | Avoid repeated freeze/thaw cycles. Store at 2-8°C for short term. Aliquot and store at -20°C for long term storage. |
| Size | 1 set |
| Sample Type | Serum; Plasma; Cell Culture Supernatant |
| Usage Statement | Available for Research Use Only. Not for use in therapeutic or diagnostic applications. |
Target Overview | |
|---|---|
| Gene Symbol | DBI |
| Full Name | Diazepam Binding Inhibitor (DBI) |
| Background | This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] |
| Alternative Names | Diazepam Binding Inhibitor; Acyl-CoA Binding Protein; Endozepine; Diazepam Binding Inhibitor (GABA Receptor Modulator; Acyl-Coenzyme A Binding Protein); Diazepam-Binding Inhibitor; ACBP; EP; Diazepam Binding Inhibitor (GABA Receptor Modulator; Acyl-CoA Binding Protein); Cholecystokinin-Releasing Peptide; Trypsin-Sensitive; |
| Gene ID | 1622(Human); 13167(Mouse); 25045(Rat) |
| Uniprot ID | P07108(Human); P31786(Mouse); P11030(Rat) |
For Research Use Only.
Application
