Human FGL2 Matched Antibody Pair set for ELISA useCapture Antibody: Rabbit purified polyclonal anti-FGL2Detection Antibody: Mouse monoclonal anti-FGL2, IgG2a Kappa
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Antigen Detail | |
|---|---|
| Target | FGL2 |
| Description | Fibrinogen-like protein 2, also known as FGL2, is a protein which in humans is encoded by the FGL2 gene. FGL2 expression is a novel, independent, and an adverse prognostic factor of clinical outcomes in patients with clear cell renal cell carcinoma. Serum FGL2 is a promising biomarker for assessing the severity and prognosis in severe TBI FGL2 promotes tumor progression in the brain by suppressing CD103-expressing dendritic cell differentiation. |
| Species Reactivity | Human |
Capture Antibody | |
|---|---|
| Capture Clonality | Polyclonal |
| Host Species | Rabbit |
| Purification | Affinity chromatography |
| Buffer | PBS, pH 7.4, containing 0.1% Proclin 300 |
| Application | ELISA |
Detection Antibody | |
|---|---|
| Det-Clonality | Monoclonal |
| Host Species | Mouse |
| Conjugation | Unconjugated |
| Clone | RD10170 |
| Isotype | IgG2a, kappa |
| Purification | Affinity chromatography |
| Buffer | PBS, pH 7.4 |
General Product Property | |
|---|---|
| Product Overview | Human FGL2 Matched Antibody Pair set for ELISA use Capture Antibody: Rabbit purified polyclonal anti-FGL2 Detection Antibody: Mouse monoclonal anti-FGL2, IgG2a Kappa |
| Specificity | Validated for detecting natural and recombinant human FGL2 |
| Research Area | Immunology |
| Application | ELISA |
| Application Notes | Optimal dilutions should be determined experimentally by the user. |
| Form | Lyophilized |
| Storage | Avoid repeated freeze/thaw cycles. Store at 2-8°C for short term. Aliquot and store at -20°C for long term storage. |
| Size | 1 Set |
| Sample Type | Serum; Supernatant; Urine; Cell lysate; Plasma; Tissue Homogenates |
| Usage Statement | Available for Research Use Only. Not for use in therapeutic or diagnostic applications. |
Target Overview | |
|---|---|
| Gene Symbol | FGL2 |
| Full Name | Fibrinogen Like 2 |
| Background | The protein encoded by this gene is a secreted protein that is similar to the beta- and gamma-chains of fibrinogen. The carboxyl-terminus of the encoded protein consists of the fibrinogen-related domains (FRED). The encoded protein forms a tetrameric complex which is stabilized by interchain disulfide bonds. This protein may play a role in physiologic functions at mucosal sites. [provided by RefSeq, Jul 2008] |
| Alternative Names | Fibroleukin; T49 |
| Gene ID | 10875 |
| Uniprot ID | Q14314 |
| GeneCards | FGL2 |
| HGNC | 3696 |
| Ensembl | ENSG00000127951 |
| OMIM | 605351 |
| Involvement in Disease | Diseases associated with FGL2 include Viral Hepatitis and Acute Liver Failure. |
| Function | May play a role in physiologic lymphocyte functions at mucosal sites. |
| Related Pathways | Its related pathways are Innate Immune System. |
For Research Use Only.
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