Name: Human Galectin-1 ELISA Matched Antibody Pair Set [ABP-Q-04-262]
SKU: ABP-Q-04-262
Price: 919.6 USD

Human Galectin-1 ELISA Matched Antibody Pair Set [ABP-Q-04-262] (CAT#: ABP-Q-04-262)

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Human Galectin-1 antibody pair set for ELISA useCapture Antibody: rabbit anti-Galectin-1 monoclonal antibodyDetection Antibody: rabbit anti-Galectin-1 monoclonal antibody conjugated to HRP

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Type	Size	Price	Quantity
Antibody Pair Set-Package 1	5 × 96 tests	$919.60
Antibody Pair Set-Package 2	15 × 96 tests	$1,919.66

Datasheet

MSDS

Certificate of Analysis Lookup

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Lot Number

Antigen Detail
Target	Galectin-1
Description	Galectin-1 (Gal-1, GAL1), is a member of the galectins, a family of animal lectins ranging from Caenorhabditis elegans to humans, which is defined by their affinity for beta-galactosides and by significant sequence similarity in the carbohydrate-binding site. It is a homodimer with a subunit molecular mass of 14.5 kDa, which contains six cysteine residues per subunit. The cysteine residues should be in a free state to maintain a molecular structure that is capable of showing lectin activity. This endogenous lectin widely expressed at sites of inflammation and tumor growth has been postulated as an attractive immunosuppressive agent to restore immune cell tolerance and homeostasis in autoimmune and inflammatory settings. On the other hand, galectin-1 contributes to different steps of tumor progression including cell adhesion, migration, and tumor-immune escape, suggesting that blockade of galectin-1 might result in therapeutic benefits in cancer. Several potential glycoprotein ligands for galectin-1 have been identified, including lysosome-associated membrane glycoproteins and fibronectin, laminin, as well as T-cell glycoproteins CD43 and CD45. Evidence points to Gal-1 and its ligands as one of the master regulators of such immune responses as T-cell homeostasis and survival, T-cell immune disorders, inflammation, and allergies as well as host-pathogen interactions.
Species Reactivity	Human

Capture Antibody
Capture Clonality	Monoclonal
Host Species	Rabbit
Clone	IV01628
Purification	Affinity Chromatography
Buffer	Prior to lyophilization: PBS, pH 7.4
Application	ELISA

Detection Antibody
Det-Clonality	Monoclonal
Host Species	Rabbit
Conjugation	HRP
Clone	RD10362
Purification	Affinity Chromatography
Buffer	Prior to lyophilization: PBS, containing 50 % HRP-Protector

General Product Property
Product Overview	Human Galectin-1 antibody pair set for ELISA use Capture Antibody: rabbit anti-Galectin-1 monoclonal antibody Detection Antibody: rabbit anti-Galectin-1 monoclonal antibody conjugated to HRP
Specificity	Quantitative determination of Human Galectin-1
Range	312.5-20000 pg/mL
Research Area	Cell-matrix interactions; Apoptosis
Application	ELISA
Application Notes	Optimal dilutions should be determined experimentally by the user.
Form	Lyophilized
Storage	Avoid repeated freeze/thaw cycles. Store at 2-8°C for short term. Aliquot and store at -20°C for long term storage.
Size	1 Set
Sample Type	Serum; Supernatant; Urine; Cell lysate; Plasma; Tissue Homogenates
Usage Statement	Available for Research Use Only. Not for use in therapeutic or diagnostic applications.

Target Overview
Gene Symbol	LGALS1
Full Name	Galectin-1
Background	The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. This gene product may act as an autocrine negative growth factor that regulates cell proliferation.
Alternative Names	LGALS1; GAL1; GBP; galectin 1
Gene ID	3956
Uniprot ID	P09382

For Research Use Only.

Human Galectin-1 ELISA Matched Antibody Pair Set [ABP-Q-04-262] (CAT#: ABP-Q-04-262)

Antigen Detail

Capture Antibody

Detection Antibody

General Product Property

Target Overview