Human SFTPD antibody pair set for sandwich ELISA useCapture Antibody: Monoclonal IgGDetection Antibody: Unconjugated-Rabbit Monoclonal IgG
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Antigen Detail | |
|---|---|
| Target | SFTPD |
| Description | Surfactant protein D, also known as SP-D, is a lung surfactant protein part of the collagenous family of proteins called collectin.[5] In humans, SP-D is encoded by the SFTPD gene[6][7] and is part of the innate immune system.[8][9] Each SP-D subunit is composed of an N-terminal domain, a collagenous region, a nucleating neck region, and a C-terminal lectin domain.[5][10] Three of these subunits assemble to form a homotrimer, which further assemble into a tetrameric complex. |
| Species Reactivity | Human |
Capture Antibody | |
|---|---|
| Capture Clonality | Monoclonal |
| Host Species | Rabbit |
| Clone | IV01922 |
| Isotype | IgG |
| Purification | Affinity Chromatography |
| Buffer | PBS, pH 7.4, containing 0.1% Proclin 300 |
| Application | ELISA |
Detection Antibody | |
|---|---|
| Det-Clonality | Monoclonal |
| Host Species | Rabbit |
| Conjugation | Unconjugated |
| Clone | RD10262 |
| Isotype | IgG |
| Purification | Affinity Chromatography |
| Buffer | PBS, pH 7.4, BSA and Azide free |
General Product Property | |
|---|---|
| Product Overview | Human SFTPD antibody pair set for sandwich ELISA use Capture Antibody: Monoclonal IgG Detection Antibody: Unconjugated-Rabbit Monoclonal IgG |
| Specificity | Both the capture and the detection antibodies in this set react with Human SFTPD. |
| Research Area | Cardiovascular; Signal Transduction; Cancer |
| Application | ELISA |
| Application Notes | Optimal dilutions should be determined experimentally by the user. |
| Form | Liquid |
| Storage | Avoid repeated freeze/thaw cycles. Store at 2-8°C for short term. Aliquot and store at -20°C for long term storage. |
| Size | 1 Set |
| Sample Type | Plasma; Serum; Cell Culture Supernatant |
| Usage Statement | Available for Research Use Only. Not for use in therapeutic or diagnostic applications. |
Target Overview | |
|---|---|
| Gene Symbol | SFTPD |
| Full Name | Surfactant protein D |
| Background | Surfactant protein D, also known as SP-D, is a lung surfactant protein part of the collagenous family of proteins called collectin.[5] In humans, SP-D is encoded by the SFTPD gene[6][7] and is part of the innate immune system.[8][9] Each SP-D subunit is composed of an N-terminal domain, a collagenous region, a nucleating neck region, and a C-terminal lectin domain.[5][10] Three of these subunits assemble to form a homotrimer, which further assemble into a tetrameric complex. |
| Alternative Names | SFTPD; COLEC7; PSP-D; SFTP4; SP-D; surfactant protein D |
| Gene ID | 6441 |
| Uniprot ID | P35247 |
| GeneCards | SFTPD |
| HGNC | 10803 |
| Ensembl | ENSG00000133661 |
| OMIM | 178635 |
| Involvement in Disease | Diseases associated with SFTPD include Extrinsic Allergic Alveolitis and Pulmonary Alveolar Proteinosis. |
| Function | Contributes to the lung's defense against inhaled microorganisms, organic antigens and toxins. Interacts with compounds such as bacterial lipopolysaccharides, oligosaccharides and fatty acids and modulates leukocyte action in immune response. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties. |
For Research Use Only.
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