Human TEM7 ELISA Matched Antibody Pair Set [ABP-Q-04-311] (CAT#: ABP-Q-04-311)

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Human PLXDC1 antibody pair set for ELISA useCapture Antibody: mouse anti-PLXDC1 monoclonal antibodyDetection Antibody: mouse anti-PLXDC1 monoclonal antibody conjugated to HRP

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Type Size Price Quantity  
Antibody Pair Set-Package 1 5 × 96 tests $1,120.00
Antibody Pair Set-Package 2 15 × 96 tests $2,331.43
Datasheet
MSDS
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Lot Number

Antigen Detail
TargetTEM7
DescriptionPlexin domain-containing protein 1, also known as tumor endothelial marker 3, tumor endothelial marker 7 and PLXDC1 and TEM3, is a secreted, cytoplasm and single-pass type I membrane protein that belongs to the plexin family. PLXDC1 / TEM3 is detected in endothelial cells from colorectal cancer, and in endothelial cells from primary cancers of the lung, liver, pancreas, breast and brain. It is expressed in fibrovascular membrane with increased expression in individuals with proliferative diabetic retinopathy. PLXDC1 / TEM3 is not detectable in endothelial cells from normal tissue. PLXDC1 / TEM3 plays a critical role in endothelial cell capillary morphogenesis. PLXDC1 / TEM3 may play a significant role in the proliferation and maintenance of neovascular endothelial cells in the formation of fibrovascular membranes (FVMs). PLXDC1 / TEM3 may be a molecular target for new diagnostic and therapeutic strategies for proliferative diabetic retinopathy (PDR). PLXDC1 / TEM3 interacts with NID1. It may also interact with CTTN.
Species ReactivityHuman

Capture Antibody
Capture ClonalityMonoclonal
Host SpeciesMouse
CloneIV01955
PurificationAffinity Chromatography
BufferPrior to lyophilization: PBS, pH 7.4
ApplicationELISA

Detection Antibody
Det-ClonalityMonoclonal
Host SpeciesMouse
ConjugationHRP
CloneRD10143
PurificationAffinity Chromatography
BufferPrior to lyophilization: PBS, containing 50 % HRP-Protector

General Product Property
Product OverviewHuman PLXDC1 antibody pair set for ELISA use
Capture Antibody: mouse anti-PLXDC1 monoclonal antibody
Detection Antibody: mouse anti-PLXDC1 monoclonal antibody conjugated to HRP
SpecificityQuantitative determination of Human PLXDC1
Range156.25-10000 pg/mL
Research AreaEndothelial Marker
ApplicationELISA
Application NotesOptimal dilutions should be determined experimentally by the user.
FormLyophilized
StorageAvoid repeated freeze/thaw cycles. Store at 2-8°C for short term. Aliquot and store at -20°C for long term storage.
Size1 Set
Sample TypeSerum; Supernatant; Urine; Cell lysate; Plasma; Tissue Homogenates
Usage StatementAvailable for Research Use Only. Not for use in therapeutic or diagnostic applications.

Target Overview
Gene SymbolPLXDC1
Full NamePlexin Domain Containing 1
BackgroundPlays a critical role in endothelial cell capillary morphogenesis.
Alternative NamesTumor Endothelial Marker 3
Gene ID57125
Uniprot IDQ8IUK5

For Research Use Only.

Application
AgonistAgonist
AntagonistAntagonist
ApopApoptosis Assay
BlockBlocking
BIBioimaging
ChIPChromatin Immunoprecipitation
Co-IPCo-Immunoprecipitation
CytCytotoxicity Assay
CellActCell Activiation
CellDiffCell Differentiation
DBDot Blot
ECLElectrochemiluminescence
ELISAEnzyme-Linked Immunosorbent Assay
Indirect ELISAIndirect ELISA
Sandwich ELISASandwich ELISA
Competitive ELISACompetitive ELISA
ELISPOTEnzyme-linked Immunosorbent Spot
FuncSFunctional Studies
FACSFluorescence-activated cell sorting
FCFlow Cytometry
FIAFluorescence Immunoassay
FRETFluorescence Resonance Energy Transfer Microscopy
GSGel Shift
HAHemagglutination Assay
HPLCHigh Performance Liquid Chromatography
IAImmunoassay
IBImmunoblotting
ICCImmunocytochemistry
IEMImmuno-Electron Microscopy
IFImmunofluorescence
IHCImmunohistochemistry
IHC-FrImmunohistochemistry-Frozen
IHC-PImmunohistochemistry-Paraffin
IPImmunoprecipitation
IRMAImmunoradiometric Assay
ISHIn Situ Hybridization
InhibitInhibition Assay
Live-cell imagingLive-cell Imaging Assay
MeDIPMethylated DNA Immunoprecipitation
MAMicroagglutination Assay
MSMass Spectrometry
NeutNeutralization Assay
PepArrPeptide Array
PPProtein Purification
PGProteogenomics
RIRadial Immunodiffusion
RIARadioimmunoassay
RIPRadioimmunoprecipitation
StimStimulation Assay
TCAT-Cell Activation Assay
TRFTime-Resolved Fluorescence
TCTissue Culture
TBTurbidimetry
PBAProtein Binding Assay
PLAProximity Ligation Assay
SDS-PAGESodium Dodecyl Sulfate Polyacrylamide Gel Electrophoresis
SPRSurface Plasmon Resonance
WBWestern Blot
CLIAChemiluminescent Immunoassay
CLEIAChemiluminescent Enzyme Immunoassay
ECLIAElectrochemiluminescence Immunoassay
TRFIATime-resolved Fluorescence Immunoassay
LIALaser Immunoassay
MLEIAMicroparticle Luminescence Enzyme Immunoassay
LETIALatex Particle-Enhanced Turbidimetric Immunoassay
LFIALateral Flow Immunoassay
GICAColloidal Gold immunochomatography Assay
ICTImmune Chromatographic Test
LTIALatex Turbidimetric Immunoassay
CMIAChemiluminescence microparticle immuno assay
IACInnuno-Affinity Chromatography
TIATurbidimetric Immunoassay
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