Mouse IL-2 antibody pair set for ELISPOT useCapture Antibody: Rat Monoclonal IgGDetection Antibody: Rat Monoclonal IgG
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Antigen Detail | |
|---|---|
| Target | IL-2 |
| Description | Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system. It is a 15.5-16 kDa protein[5] that regulates the activities of white blood cells (leukocytes, often lymphocytes) that are responsible for immunity. IL-2 is part of the body's natural response to microbial infection, and in discriminating between foreign ("non-self") and "self". IL-2 mediates its effects by binding to IL-2 receptors, which are expressed by lymphocytes. The major sources of IL-2 are activated CD4+ T cells and activated CD8+ T cells. |
| Species Reactivity | Mouse |
Capture Antibody | |
|---|---|
| Capture Clonality | Monoclonal |
| Host Species | Rat |
| Clone | IV01197 |
| Isotype | IgG |
| Purification | Affinity Chromatography |
| Buffer | Preservative-free PBS, pH 7.2 |
| Application | ELISA |
Detection Antibody | |
|---|---|
| Det-Clonality | Monoclonal |
| Host Species | Rat |
| Conjugation | Biotin |
| Clone | RD1029 |
| Isotype | IgG |
| Purification | Affinity Chromatography |
| Buffer | PBS, pH 7.2, containing 0.09% sodium azide |
General Product Property | |
|---|---|
| Product Overview | Mouse IL-2 antibody pair set for ELISPOT use Capture Antibody: Rat Monoclonal IgG Detection Antibody: Rat Monoclonal IgG |
| Specificity | Both the capture and the detection antibodies in this set react with mouse IL2 protein. |
| Research Area | Inflammation |
| Application | ELISPOT |
| Application Notes | Optimal dilutions should be determined experimentally by the user. |
| Form | Liquid |
| Storage | Avoid repeated freeze/thaw cycles. Store at 2-8°C for short term. Aliquot and store at -20°C for long term storage. |
| Size | 1 Set |
| Sample Type | Plasma; Serum; Cell Culture Supernatant |
| Usage Statement | Available for Research Use Only. Not for use in therapeutic or diagnostic applications. |
Target Overview | |
|---|---|
| Gene Symbol | IL2 |
| Full Name | Interleukin 2 |
| Background | Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system. It is a 15.5-16 kDa protein[5] that regulates the activities of white blood cells (leukocytes, often lymphocytes) that are responsible for immunity. IL-2 is part of the body's natural response to microbial infection, and in discriminating between foreign ("non-self") and "self". IL-2 mediates its effects by binding to IL-2 receptors, which are expressed by lymphocytes. The major sources of IL-2 are activated CD4+ T cells and activated CD8+ T cells. |
| Alternative Names | IL2; IL-2; TCGF; lymphokine; interleukin 2 |
| Gene ID | 3558 (Human) |
| Uniprot ID | P60568 (Human) |
| GeneCards | IL2 |
| HGNC | 6001 |
| Ensembl | ENSG00000109471 |
| OMIM | 147680 |
| Involvement in Disease | Diseases associated with IL2 include Capillary Leak Syndrome and Tropical Spastic Paraparesis. |
| Function | Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. |
| Related Pathways | Its related pathways pathways are RET signaling and Signaling by GPCR. |
For Research Use Only.
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