Name: Mouse IL1A ELISA Matched Antibody Pair Set [ABP-Q-04-223]
SKU: ABP-Q-04-223
Price: 919.6 USD

Mouse IL1A ELISA Matched Antibody Pair Set [ABP-Q-04-223] (CAT#: ABP-Q-04-223)

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Mouse IL1A antibody pair set for ELISA useCapture Antibody: rabbit anti-Mouse IL1A monoclonal antibodyDetection Antibody: rabbit anti-Mouse IL1A polyclonal antibody conjugated to HRP

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Type	Size	Price	Quantity
Antibody Pair Set-Package 1	5 × 96 tests	$919.60
Antibody Pair Set-Package 2	15 × 96 tests	$1,919.66

Datasheet

MSDS

Certificate of Analysis Lookup

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Lot Number

Antigen Detail
Target	IL1A
Description	IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation, and cell survival/apoptosis but are also involved in several pathophysiological processes including viral infections and autoimmune diseases. Cytokines are synthesized under various stimuli by a variety of cells of both the innate (monocytes, macrophages, dendritic cells) and adaptive (T- and B-cells) immune systems. Cytokines can be classified into two groups: pro- and anti-inflammatory. Pro-inflammatory cytokines, including IFNgamma, IL-1, IL-6, and TNF-alpha, are predominantly derived from the innate immune cells and Th1 cells. Anti-inflammatory cytokines, including IL-10, IL-4, IL-13, and IL-5, are synthesized from Th2 immune cells. IL-1 alpha is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. It is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. IL-1 alpha stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity.
Species Reactivity	Mouse

Capture Antibody
Capture Clonality	Monoclonal
Host Species	Mouse
Clone	IV0190
Purification	Affinity Chromatography
Buffer	Prior to lyophilization: PBS, pH 7.4
Application	ELISA

Detection Antibody
Det-Clonality	Polyclonal
Host Species	Rabbit
Conjugation	HRP
Purification	Affinity Chromatography
Buffer	Prior to lyophilization: PBS, containing 50 % HRP-Protector

General Product Property
Product Overview	Mouse IL1A antibody pair set for ELISA use Capture Antibody: rabbit anti-Mouse IL1A monoclonal antibody Detection Antibody: rabbit anti-Mouse IL1A polyclonal antibody conjugated to HRP
Specificity	Quantitative determination of Mouse IL1A
Range	6.25-400 pg/mL
Research Area	Innate Immunity
Application	ELISA
Application Notes	Optimal dilutions should be determined experimentally by the user.
Form	Lyophilized
Storage	Avoid repeated freeze/thaw cycles. Store at 2-8°C for short term. Aliquot and store at -20°C for long term storage.
Size	1 Set
Sample Type	Serum; Supernatant; Urine; Cell lysate; Plasma; Tissue Homogenates
Usage Statement	Available for Research Use Only. Not for use in therapeutic or diagnostic applications.

Target Overview
Gene Symbol	IL1A
Full Name	interleukin 1, alpha
Background	The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.
Alternative Names	IL-1 alpha; Interleukin-1 alpha; IL1; IL1F1; Hematopoietin-1; IL1-ALPHA; IL-1A
Gene ID	3552
Uniprot ID	P01583

For Research Use Only.

Mouse IL1A ELISA Matched Antibody Pair Set [ABP-Q-04-223] (CAT#: ABP-Q-04-223)

Antigen Detail

Capture Antibody

Detection Antibody

General Product Property

Target Overview