Name: Rat CD86 ELISA Matched Antibody Pair Set [ABP-Q-04-86]
SKU: ABP-Q-04-86
Price: 919.6 USD

Rat CD86 ELISA Matched Antibody Pair Set [ABP-Q-04-86] (CAT#: ABP-Q-04-86)

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Rat CD86 antibody pair set for ELISA useCapture Antibody: mouse anti-CD86 monoclonal antibodyDetection Antibody: mouse anti-CD86 monoclonal antibody conjugated to HRP

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Type	Size	Price	Quantity
Antibody Pair Set-Package 1	5 × 96 tests	$919.60
Antibody Pair Set-Package 2	15 × 96 tests	$1,919.66

Datasheet

MSDS

Certificate of Analysis Lookup

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Lot Number

Antigen Detail
Target	CD86
Description	CD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominantly as a monomer on cell surfaces and interacts with two co-stimulatory receptors CD28 and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) expressed on T cells, and thus induces the signal pathways which regulate T cell activation and tolerance, cytokine production, and the generation of CTL. It is indicated that contacts between B and T helper cells mediated by CD86 encourage signals for the proliferation and IgG secretion of normal B cells and B cell lymphomas. A recent study has revealed that CD86 also promotes the generation of a mature APC repertoire and promotes APC function and survival. CD86 has an important role in chronic hemodialysis, allergic pulmonary inflammation, arthritis, and antiviral responses, and thus is regarded as a promising candidate for immune therapy.
Species Reactivity	Rat

Capture Antibody
Capture Clonality	Monoclonal
Host Species	Mouse
Clone	IV01652
Purification	Affinity Chromatography
Buffer	Prior to lyophilization: PBS, pH 7.4
Application	ELISA

Detection Antibody
Det-Clonality	Monoclonal
Host Species	Mouse
Conjugation	HRP
Clone	RD10393
Purification	Affinity Chromatography
Buffer	Prior to lyophilization: PBS, containing 50 % HRP-Protector

General Product Property
Product Overview	Rat CD86 antibody pair set for ELISA use Capture Antibody: mouse anti-CD86 monoclonal antibody Detection Antibody: mouse anti-CD86 monoclonal antibody conjugated to HRP
Specificity	Quantitative determination of Rat CD86
Range	4.69-300 pg/mL
Research Area	Innate Immunity
Application	ELISA
Application Notes	Optimal dilutions should be determined experimentally by the user.
Form	Lyophilized
Storage	Avoid repeated freeze/thaw cycles. Store at 2-8°C for short term. Aliquot and store at -20°C for long term storage.
Size	1 Set
Sample Type	Serum; Supernatant; Urine; Cell lysate; Plasma; Tissue Homogenates
Usage Statement	Available for Research Use Only. Not for use in therapeutic or diagnostic applications.

Target Overview
Gene Symbol	CD86
Full Name	CD86
Background	Cluster of Differentiation 86 (also known as CD86 and B7-2) is a protein expressed on dendritic cells, macrophages, B-cells, and other antigen-presenting cells. Along with CD80, CD86 provides costimulatory signals necessary for T-cell activation and survival. Depending on the ligand bound, CD86 can be used to signal for self-regulation and cell-cell association, or for attenuation of regulation and cell-cell disassociation.
Alternative Names	CD86; CD86 molecule
Gene ID	942
Uniprot ID	P42081

For Research Use Only.

Rat CD86 ELISA Matched Antibody Pair Set [ABP-Q-04-86] (CAT#: ABP-Q-04-86)

Antigen Detail

Capture Antibody

Detection Antibody

General Product Property

Target Overview