Tyrosine Phosphorylation ProArray features 228 high-specificity site-specific phospho-tyrosine antibodies, specifically optimized for site-specific tyrosine phosphorylation profiling in human, mouse, and rat cell and tissue samples. Each kit includes two identical array slides, enabling parallel analysis of two independent samples, such as a control specimen and a treated experimental sample.
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Product Property | |
|---|---|
| Species Reactivity | Human; Mouse; Rat |
| Sample Type | Cell lysate; Tissue lysate |
| Assay Type | Fluorescent Immunoassay |
| Detection Method | Fluorescence Scanning |
| Internal Controls | Beta-actin; GAPDH; Negative controls |
| Principle | Fluorescent immunoassay based on antibody microarray, for quantitative detection of tyrosine pathway phosphorylation levels. |
| Platform | Fluorescent Antibody Microarray |
| Specificity | Human |
| Cross-Reaction | Mouse; Rat |
| Slide Dimensions | 76 x 25 x 1 mm |
| Application Notes | ELISA based antibody array |
| Core Highlights | Site-specific tyrosine phosphorylation profiling and screening with 228 antibodies Antibodies covalently immobilized on 3D polymer coated glass slide Fluorescent detection |
| Signaling Pathway | Tyrosine Signaling Pathway |
| Storage | 2-8°C |
Target Information | |
|---|---|
| Analyte | Tyrosine Pathway Phosphoproteins |
| Targets | Abl1 (pTyr204), Abl1 (pTyr412), ACK1 (pTyr284), ACTIN Pan (a/b/g) (pTyr55/53), AKT (pTyr326), AKT1 (pTyr474), ALK (pTyr1507), ALK (pTyr1604), A-RAF (pTyr301/302), AurB (pTyr12), AXL (pTyr691), Bcr (pTyr177), BCR (pTyr360), BLNK (pTyr84), BLNK (pTyr96), Breast tumor kinase (pTyr447), BTK (pTyr222), BTK (pTyr550), c-Abl (pTyr245), c-Abl (pTyr412), Caspase 9 (pTyr153), Catalase (pTyr385), Catenin beta (pCTNNB) (pTyr489), Catenin beta (pTyr654), Catenin delta-1 (pTyr228), Caveolin-1 (pTyr14), CBL (pTyr700), CBL (pTyr774), CD19 (pTyr531), CD22/BL-CAM (pTyr807), CD227/mucin 1 (pTyr1243), CD28 (pTyr218), CD3Z (pTyr142), CD5 (pTyr453), CDC2 (pTyr15), CDK5 (pTyr15), c-Jun (pTyr170), CK1-A/A2 (pTyr294), c-Kit (pTyr721), claudin 3 (pTyr219), claudin 6 (pTyr219), claudin 7 (pTyr210), c-met (pTyr1003), Cortactin (pTyr421), Cortactin (pTyr466), CrkII (pTyr221), CrkL (pTyr207), CSFR (pTyr561), Dab1 (pTyr220), Dab1 (pTyr232), DAPP1 (pTyr139), DDX5/DEAD-box protein 5 (pTyr593), Dok1 (pTyr362), Dok1 (pTyr398), Dok2 (pTyr299), EGFR (pTyr1016), EGFR (pTyr1069), EGFR (pTyr1092), EGFR (pTyr1110), EGFR (pTyr1172), EGFR (pTyr1197), EGFR (pTyr869), EPB41 (pTyr418/660), EPHA2/3/4 (pTyr588/596), EPHB1/2 (pTyr594/604), Ephrin B (pTyr330), Ephrin B1/B2/B3 (pTyr324), Ephrin-B1 (pTyr317), Epo-R (pTyr368), ERK8 (pThr175/177), Etk (pTyr40), ETK (pTyr566), Ezrin (pTyr353), ezrin (pTyr478), FAK (pTyr397), FAK (pTyr407), FAK (pTyr576), FAK (pTyr861), FAK (pTyr925), FER (pTyr402), FGFR1 (pTyr154), FGFR1 (pTyr654), FGFR1 (pTyr766), FLT3 (pTyr842), FLT3 (pTyr969), FRS2 (pTyr436), Fyn (pTyr530), Gab1 (pTyr627), Gab1 (pTyr659), Gab2 (pTyr643), GRB10 (pTyr67), GRF-1 (pTyr1105), GSK3a-b (pTyr216/279), HCK (pTyr410), HER2 (pTyr1221/1222), HER2 (pTyr1248), HER2 (pTyr877), HER3/ErbB3 (pTyr1222), HER3/ErbB3 (pTyr1289), HER4/ErbB4 (pTyr1284), HRS (pTyr334), ICAM-1 (pTyr512), ICK (pTyr159), IGF-1R (pTyr1161), IGF-1R (pTyr1165/1166), IkB-alpha (pTyr305), IkB-alpha (pTyr42), IKK-beta (pTyr188), IKK-beta (pTyr199), IL-10R-A (pTyr496), IL-13R/CD213a1 (pTyr405), IL3R (pTyr593), IL-4R/CD124 (pTyr497), IL7R/CD127 (pTyr449), Integrin b3 (pTyr773), Integrin b3 (pTyr785), IFN-gamma receptor alpha chain precursor (pTyr457), IR (pTyr1355), IR (pTyr1361), ITGB4 (pTyr1510), JAK1 (pTyr1022), JAK2 (pTyr1007), JAK2 (pTyr221), JNK1/2/3 (pThr183/Tyr185), KIT (pTyr703), KIT (pTyr936), Kv1.3/KCNA3 (pTyr135), Kv2.1/Kcnb1 (pTyr128), LAT (pTyr171), LAT (pTyr191), LCK (pTyr192), LCK (pTyr393), LCK (pTyr504), LYN (pTyr507), M-CSF Receptor (pTyr809), MER/SKY (pTyr749/681), Met (pTyr1234), Met (pTyr1349), Met (pTyr1356), NMDA NR2A/B (pTyr1246/1252), NMDAR2B (pTyr1472), p130Cas (pTyr165), p130Cas (pTyr410), p38 MAPK (pTyr182), p38 MAPK (pTyr322), p44/42 MAPKinase (pTyr204), p73 (pTyr99), Paxillin (pTyr118), Paxillin (pTyr31), PDGF-R alpha (pTyr849), PDGF-R beta (pTyr1021), PDGF-R beta (pTyr740), PDGF-R beta (pTyr751), PECAM-1 (pTyr713), PI3-kinase p85-alpha (pTyr607), PI3-kinase p85-subunit a/g (pTyr467/199), Pim-1 (pTyr309), PKC alpha (pTyr657), PKC delta (pTyr52), PKC delta (pTyr313), PKC delta/PKCD (pTyr64), PKD1/PKC mu (pTyr463), PLCG1 (pTyr1253), PLCG1 (pTyr771), PLCG1 (pTyr783), PLCG2 (pTyr1217), PLCG2 (pTyr753), PLD2 (pTyr169), PP2A-a (pTyr307), PTPRA (pTyr798), Pyk2 (pTyr402), Pyk2 (pTyr579), Pyk2 (pTyr580), Pyk2 (pTyr881), RAD51 (pTyr315), RAD52 (pTyr104), Raf1 (pTyr341), RapGEF1 (pTyr504), Ret (pTyr905), RGS16 (pTyr168), SAPK/JNK (pTyr185), Shc (pTyr349), Shc (pTyr427), SHP-1 (pTyr536), SHP-2 (pTyr542), SHP-2 (pTyr580), SLP-76 (pTyr128), Src (pTyr216), Src (pTyr418), Src (pTyr529), STAM2 (pTyr192), STAT1 (pTyr701), STAT2 (pTyr690), STAT3 (pTyr705), STAT4 (pTyr693), STAT5A (pTyr694), STAT6 (pTyr641), SYK (pTyr323), SYK (pTyr348), SYK (pTyr525), Synuclein alpha (pTyr125), Synuclein alpha (pTyr133), Synuclein alpha (pTyr136), TFII-I (pTyr248), TIE2 (pTyr1108), Trk A (pTyr680/681), Trk A (pTyr701), Trk A (pTyr791), Trk B (pTyr515), Trk B (pTyr705), TYK2 (pTyr1054), Vav1 (pTyr174), Vav2 (pTyr142), VE-Cadherin (pTyr731), VEGFR1 (pTyr1333), VEGFR2 (pTyr1054), VEGFR2 (pTyr1059), VEGFR2 (pTyr1175), VEGFR2 (pTyr1214), VEGFR2 (pTyr951), Vinculin (pTyr821), WASP (pTyr290), WAVE1 (pTyr125), WWOX (pTyr33), ZAP-70 (pTyr292), ZAP-70 (pTyr315), ZAP-70 (pTyr319), ZAP-70 (pTyr493) |
| Target Source | Human; Mouse; Rat |
For Research Use Only.