As a pioneer in the in vitro diagnostic (IVD) field, Creative Biolabs focuses on providing quality and innovative antibodies for IVD use to meet the laboratory research and even further serve the clinical market. We provide cutting-edge IVD antibody-based diagnostics to the anatomic pathology and histology market. Our services portfolio includes not only antibody development service, but also antigen and antibody conjugation, and IVD kit development service.
Polyclonal antibodies can be used in the in vitro assays in many different formats. The formats of the application range from sophisticated flow cytometry (FCM) to simple enzyme-linked immunosorbent assay (ELISA). The results of antibody-facilitated assays are often used to support a tentative clinical diagnosis, evaluate disease progression, and provide prognostic information. A wide range of in vitro assays are also capable to determine the presence of bacteria, viruses, and antigens.
Polyclonal antibody production remains an essential research activity. Creative Biolabs has years of experience in this field by providing an enormous variety of antibody development services for different hosts, including rabbit polyclonal antibodies, goat polyclonal antibodies, chicken polyclonal antibodies, and so on.
Rabbit Polyclonal Antibody Development
Rabbits serve as the primary host of choice for producing polyclonal antibodies. Immunogen, the adjuvant, and the end purpose of the antibody play important roles in the schedules and methodologies to immunize rabbits and produce polyclonal antibodies. The choices of adjuvant and immunization schedules are critical in the polyclonal antibody production process. Our rabbit polyclonal antibody development service is based on a strong foundation that we built over seven years of process optimization and a strong reputation of being the most reliable antibody production service provider worldwide. We have been a preferred partner for antibody development and production service for multiple top-10 pharmaceutical companies. We have attracted customers and business through word-of-mouth.
Goat Polyclonal Antibody Development
Goat is one of the species often used in polyclonal antibody production in larger amounts. The goat produces about 7-8 times the amount of serum compared to the rabbit. Furthermore, the goat serum contains about 20 mg/mL of total IgG, which is about 2-3 times more than rabbit serum. This makes the goat the more cost-effective choice of the two when larger amounts of antibody are required. What is more, you will receive material from a single animal, rather than several different individuals. In terms of antibody amounts, the chicken is the only economical rival. The goat is an ideal choice as a host species for antibody production when large amounts of antiserum are desired. Large volumes of goat antibodies are an essential tool for immunodiagnostic kits.
Chicken Polyclonal Antibody Development
Serving as hosts for polyclonal antibody production, chickens are becoming increasingly popular. There is no doubt that chicken antibodies have several merits. Our comprehensive array of custom antibody services cover from a customizable option for chicken immunization, egg-collection to titer analysis for chicken antibody production. Chickens produce large amounts of antibody (IgY) in their eggs, making them very cost effective. A single egg yolk contains about 100 mg of total IgY. This is comparable to the approximate amount of total IgG in 5 mL goat antiserum or 10 mL rabbit antiserum. Due to the evolutionary differences, chickens may respond better than rabbits or goats to highly conserved mammalian antigens. The chicken antibodies do not bind to the mammalian Fc receptor; which means very low background signals. IgY does not react with Rheumatoid Factors in mammalian serum which can cause false positives when analyzing auto-immune disease serum. IgY does not activate the mammalian complement pathway.
Creative Biolabs is a most reliable and cost-effective antibody development partner. In order to improve the value of these antibody-based diagnostic tools and help clinicians in the diagnosis, prognosis, and staging of diseases, we provide IVD antibody development services to produce high quality and affordable polyclonal antibodies of diagnostic use. We also design multiple service packages that can fit perfectly into various customer's requirements. With a full battle of quality control testing, our service includes ranging from antigen design to purified antibody product. We offer both protein A affinity purified polyclonal antibody service and antigen purified polyclonal antibody development service. In addition, we offer western blot (WB) guaranteed polyclonal antibody development service and immunohistochemistry (IHC) guaranteed polyclonal antibody development service with the support of our antibody validation platform.
If you are interested in our services, contact us to discuss your specific requirements.
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