With the commitment of being your best services provider, Creative Biolabs is capable of providing our clients with different kinds of customized in vitro diagnostics (IVD) solutions during the process of disease research. Equipped with a team of professional scientists, we have won a good reputation among our worldwide customers for accomplishing numerous challenging projects in this field. In our company, our scientists specialized in many kinds of cell level detection studies, such as thinprep cytologic test (TCT), will work with you to develop the most appropriate strategy that will offer reproducible data for your research.

Introduction to Thinprep Cytologic Test

TCT is a liquid-based cytology detection that has been broadly used in screening cervical cancer in different countries. Pilot studies have demonstrated that early diagnosis of cervical cancer by using TCT can significantly improve the cure rate and reduce the cost of later treatment. In general, the whole TCT system is composed of a sampling device, processing equipment, an imaging device, as well as an imaging analysis device. The samples will be collected and immersed in a tube containing specific preservative solutions. Afterward, the vial will be placed into the processing equipment to make sure cell samples are well-mixed. The cells are then collected by a TCT filter to distribute them evenly on a glass slide. The slide will automatically be deposited into the imaging and analysis device to obtain final data. Up to now, the TCT system has become the most popular cell-level detection method in clinical pathological practice. Studies involving thousands of female samples have indicated that TCT technology can increase the detection of precancerous cells compared to traditional cytological tests.

Thinprep cytologic test (TCT) revealed round or oval cells with pale cytoplasm and open chromatin and several small nucleoli.Fig.1 Thinprep cytologic test (TCT) revealed round or oval cells with pale cytoplasm and open chromatin and several small nucleoli. (Foster, 2016)

Our Thinprep Cytologic Test Services

Currently, TCT screening has been regarded as the primary screening method for finding early signs of cervical cancer. In the past few years, TCT technology has played a significant role in reducing the number of deaths from cervical cancer. As a result, Creative Biolabs has developed a wide variety of cell-level cytological test platform for helping different types of disease diagnosis during the novel drug discovery process.

Nowadays, we can provide a battery of traditional TCT technology services, including thinprep Pap test, TCT kits, and thinprep liquid-based cytology test. For example, in our traditional pap test, cell samples from different sources will be collected by a special brush and fixed on the glass slide. This approach can remove contaminants, such as blood and mucus, to make it easier to examine them under a microscope. This leads to a significant improvement in the detection rate of abnormal cells. Besides, we have also generated a novel liquid-based TCT technology to reduce several technical issues inherent in the conventional cytological methods. Using our novel TCT technology, the background and cell structure of thin layer smears are shown more clearly. Furthermore, the image analyzer and morphometric system can be utilized for the quantitative detection of various types of abnormal cells cost-effectively. Thus our new cytological test platform is expected to become a new auxiliary means of cytological diagnosis.

Creative Biolabs is a leading services provider, offering a wide spectrum of TCT technologies for disease diagnosis. With our cell-level cytological test platform, we are ready to help you tackle your toughest research challenge. If you are interested in our services, please contact us for closer communication to learn how we can be involved in your project. Separate services or integrated end-to-end solutions are all welcomed.


  1. Foster, H. J., et al. Primitive myxoid mesenchymal tumor of the infancy in the abdominal cavity: Report of a rare case. Pediatric and Developmental Pathology. 2016, 19: 244-248.

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