Gramicidin A TFA, Antimicrobial Peptide (AMP) (CAT#: BMWJ-0826-WJ159)
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Gramicidin A (TFA) is a peptide component of gramicidin, an antibiotic mixture originally isolated from B. brevis. Gramicidin A (TFA) is a highly hydrophobic channel-forming ionophore that forms channels in model membranes that are permeable to monovalent cations. Gramicidin A (TFA) induces degradation of hypoxia inducible factor 1 α (HIF-1α).
| Overview | |
|---|---|
| Synonyms | Gramicidin A TFA; Gramicidin A; Gramicidin A1 |
| Source | Bacteria |
| CAS | 1405-97-6 |
| Molecular Formula | C99H140N20O17 |
| Molecular Weight | 1882.29 |
| Sequence | {For}-Val-Gly-Ala-{d-Leu}-Ala-{d-Val}-Val-{d-Val}-Trp-{d-Leu}-Trp-{d-Leu}-Trp-{d-Leu}-T rp-{MEA} |
| Sequence Shortening | {For}-VGA-{d-Leu}-A-{d-Val}-V-{d-Val}-W-{d-Leu}-W-{d-Leu}-W-{d-Leu}-W-{MEA} |
| Activity | Gram-positive bacteria; Gram-negative bacteria; Ion channel; Pore formation; Valinomycin-like |
| Physical State | Powder |
| Purity | >98% |
| Storage | The power can be stored at 4°C for 2 years or at -20°C for 3 years. |
For Research Use Only.
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