Human α-defensin 6, Antimicrobial Peptide (AMP) (CAT#: BMWJ-0826-WJ444)
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Human α-Defensin 6, a 32-residue cysteine-rich peptide, can inhibit bacterial invasion and contribute to the mucosal immunity. Human α-Defensin 6 forms ordered self-assembly fibrils and nanonets that surround and entangle bacteria after stochastic binding to bacterial surface proteins. Human α-Defensin 6 also inhibits C. albicans biofilm formation.
| Overview | |
|---|---|
| Synonyms | Human α-Defensin 6; HD-6; DEFA6 |
| Source | Human |
| Sequence | Ala-Phe-Thr-Cys-His-Cys-Arg-Arg-Ser-Cys-Tyr-Ser-Thr-Glu-Tyr-Ser-Tyr-Gly-Thr-Cys-Th r-Val-Met-Gly-Ile-Asn-His-Arg-Phe-Cys-Cys-Leu (Disulfide bridge: Cys4-Cys31, Cys6-Cy s20, Cys10-Cys30) |
| Sequence Shortening | AFTCHCRRSCYSTEYSYGTCTVMGINHRFCCL (Disulfide bridge: Cys4-Cys31, Cys6-Cys20, Cys10-Cys30) |
| Activity | Gram-positive bacteria; Gram-negative bacteria; Fungi; Virus; Cancer; Human |
| Physical State | Powder |
| Purity | >98% |
| Storage | The power can be stored at 4°C for 2 years or at -20°C for 3 years. |
For Research Use Only.
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