JAK/STAT Pathway-ISRE Reporter Kit (CAT#: ZL-1123-WR10)

Overview
DescriptionThe kit contains a transfection-ready ISRE luciferase reporter vector and a negative control vector. The reporter vector contains a firefly luciferase gene under the control of a multimerized ISRE-responsive element located upstream of a minimal promoter.
FeaturesReady-used for cell signaling pathway assay.
ApplicationsKit is used to study the activity of Type I interferon-induced JAK/STAT signaling pathway in the cultured cells
Application Notes• Monitor IFNa-induced JAK/STAT signaling pathway activity.
• Screen for activators or inhibitors of the JAK/STAT signaling pathway.
• Study effects of RNAi or gene overexpression on the activity of the JAK/STAT pathway.
Research AreasDrug Discovery; Immunology; Oncology
Specification
Size500 reactions
ComponentsReporter: ISRE luciferase reporter vector & Renilla luciferase vector
Negative Control Reporter: Non-inducible luciferase vector & Renilla luciferase vector
TargetJAK/STAT
FormatSupplied with reporter vector group and negative control vector group.
StorageStore kit components at -20°C.
HandlingPlease place the product at proper storage condition once received.
ShippingIce packs
Regulatory StatusRUO

For Research Use Only.

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