Magainin 2, Antimicrobial Peptide (AMP) (CAT#: BMWJ-0826-WJ112)

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Magainin 2 (Magainin II) is an antimicrobial peptide (AMP) isolated from the skin of the African clawed frog Xenopus laevis. Magainin 2 displays antibiotic activity against numerous gram-negative and gram-positive bacteria. Magainin 2 also is active against protozoa. Magainin 2 exerts its cytotoxicity effects by preferential interactions with anionic phospholipids abundant in bacterial membranes.

Overview
SynonymsMagainin II; Magainin 2; Magainin-II; MSI-238
SourceAmphibian
CAS108433-95-0
Molecular FormulaC114H180N30O29S
Molecular Weight2466.90
SequenceGly-Ile-Gly-Lys-Phe-Leu-His-Ser-Ala-Lys-Lys-Phe-Gly-Lys-Ala-Phe-Val-Gly-Glu-Ile-Met- Asn-Ser
Sequence ShorteningGIGKFLHSAKKFGKAFVGEIMNS
ActivityGram-positive bacteria; Gram-negative bacteria; Fungi; Virus; Cancer; Pore formation; Amphibian
Physical StatePowder
Purity>98%
StorageThe power can be stored at 4°C for 2 years or at -20°C for 3 years.

For Research Use Only.

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