Mouse Notch1 NCID Pathway Reporter Kit (CAT#: ZL-1123-WR15)
| Overview | |
|---|---|
| Description | The kit consists of a transfection-ready expression vector for Mouse NOTCH1 with an extracellular domain and transmembrane region deletion (NOTCH1 NICD) and CSL (CBF1/RBP-Jκ) luciferase reporter vector. For the reporter vector, the firefly luciferase gene is controlled by multimerized CSL-responsive regions upstream of a modest promoter. |
| Features | Ready-used for cell signaling pathway assay. |
| Applications | Kit is used to study the Notch signaling pathway and measure the transcriptional activity of mouse Notch1 in cultured cells. |
| Application Notes | • Monitor Notch signaling pathway activity. • Study effects of RNAi or gene overexpression on the activity of Notch pathway |
| Research Areas | Drug Discovery; Immunology; Oncology |
| Specification | |
|---|---|
| Size | 500 reactions |
| Components | Reporter: CSL (CBF1/RBP-Jκ) luciferase reporter vector & Renilla luciferase vector Negative Control Reporter: Non-inducible luciferase vector & Renilla luciferase vector |
| Target | Mouse Notch1 |
| Format | Supplied with reporter vector group and negative control vector group. |
| Storage | Store kit components at -20°C. |
| Handling | Please place the product at proper storage condition once received. |
| Shipping | Ice packs |
| Regulatory Status | RUO |
For Research Use Only.
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