Oncocin, Antimicrobial Peptide (AMP) (CAT#: BMWJ-0826-WJ540)
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Oncocin is an antibacterial peptide. It belongs to proline-rich antimicrobial peptides (PrAMPs). Oncocin works against Gram-negative bacteria. It has MIC values of 0.125-8 μg/mL for 34 strains and clinical isolates of Enterobacteriaceae and nonfermenters. Oncocin binds to the substrate-binding domain of the chaperone DnaK. The binding has dissociation constants in the micromolar range. This binding causes protein misfolding and aggregation and the bacteria death.
| Overview | |
|---|---|
| Synonyms | Oncocin; Oncocin peptide |
| Source | Insect |
| Sequence | Val-Asp-Lys-Pro-Pro-Tyr-Leu-Pro-Arg-Pro-Arg-Pro-Pro-Arg-Arg-Ile-Tyr-Asn-Arg-NH2 |
| Sequence Shortening | VDKPPYLPRPRPPRRIYNR-NH2 |
| Activity | Gram-negative bacteria; Gram-positive bacteria; Fungi; Virus; Cancer; Insect; DnaK; Proline-rich |
| Physical State | Powder |
| Purity | >98% |
| Storage | The power can be stored at 4°C for 2 years or at -20°C for 3 years. |
For Research Use Only.
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