PathSpecific™ Human GCN5 Assay Kit, Chemiluminescent (CAT#: ZL-0224-WR38)
| Overview | |
|---|---|
| Description | The kit is based on ELISA technology, tailored for the precise quantification of the histone acetyltransferase activity of GCN5. This kit is ideal for screening and profiling purposes in research and laboratory settings. |
| Features | Ready-used for enzymatic activity assay |
| Applications | Kit is used for compound screening and profiling. |
| Application Notes | Excellent for exploring the kinetics of enzymes, screening small molecule inhibitors, and HTS applications. |
| Research Areas | Kinase Drug Discovery; Signal Pathway; |
| Specification | |
|---|---|
| Size | 96 tests |
| Components | The kit is supplied with enough recombinant purified GCN5 enzyme (amino acids 362-837), acetyl donor, pre-coated plate with histone substrate, all the reagents necessary for assay detection and blocking buffer for 96 enzyme reactions. |
| Target | GCN5 |
| Target/Description | GCN5 (General Control of Amino Acid Synthesis, Yeast, Homolog)-like 2, also known as KAT2A or lysine acetyltransferase 2A, is a versatile enzyme that can catalyze acetyltransferase, glutaryltransferase, succinyltransferase, or malonyltransferase reactions depending on the cellular environment. It serves as a transcription regulator and plays a crucial role in histone acetylation as a part of the SAGA (SPT-ADA-GCN5 acetyltransferase) and ATAC (ADA2A containing complex) complexes, acting as a histone acetyltransferase (HAT) targeted to core histones. |
| Format | Supplied with a chemiluminescent assay kit |
| Storage | Store at the appropriate temperature as directed. |
| Handling | Please store the kit according to the storage instructions in the kit's manual upon receipt. |
| Shipping | Dry ice |
| Regulatory Status | RUO |
For Research Use Only.
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