PathSpecific™ PIM3 Assay Kit (Luminescent) (CAT#: ZL-0524-WR30)
| Overview | |
|---|---|
| Description | This kit is designed to measure PIM3 activity for screening and profiling applications. |
| Features | Ready-used for enzymatic activity assay. |
| Applications | Useful for examining enzyme kinetics and screening small molecule inhibitors for drug discovery in high throughput screening (HTS) applications. |
| Assay Measures | Luminescent |
| Research Areas | Kinase Drug Discovery; Signal Pathway; |
| Specification | |
|---|---|
| Size | 96 tests |
| Components | This kit includes enough purified recombinant PIM3 enzyme, PIM substrate (S6Ktide), ATP, and kinase assay buffer for 100 enzyme reactions. |
| Target | PIM3 |
| Target/Description | PIM kinases (PIM1, PIM2, and PIM3) are serine/threonine protein kinases that are involved in key cellular processes like cell survival, proliferation, and drug resistance. These kinases are frequently upregulated in various cancers and contribute to tumor growth and cell survival by regulating cell cycle progression and preventing apoptosis. |
| Format | Luminescent Assay Kit |
| Storage | Store at the appropriate temperature as directed. |
| Handling | Please handle the product at appropriate storage condition once received. |
| Shipping | Dry ice |
| Regulatory Status | RUO |
For Research Use Only.
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