PathSpecific™ Total NAD and NADH Assay Kit-Colorimetric (Enhanced Sensitivity) (CAT#: ZL-0725-WR14)

Datasheet
Overview
DescriptionCreative Biolabs' PathSpecific™ Total NAD and NADH Assay Kit-Colorimetric (Enhanced Sensitivity) provides a convenient and highly sensitive method to directly detect NAD and NADH in biological sample mix without purification.
FeaturesConvenient, highly sensitive, simple
ApplicationsTo detect NAD and DADH in biological sample mix.
Assay MeasuresColorimetric
Research AreasCell metabolism assay; Drug discovery;
Absorbance460 nm
Specification
Size1 EA
TargetTotal NAD and NADH
Target/DescriptionNAD+ is a crucial molecule with far-reaching roles beyond its well-known function in energy metabolism. Primarily, it acts as a redox carrier, accepting hydride ions from metabolic pathways like glycolysis and the TCA cycle to form NADH, which then fuels ATP synthesis through OXPHOS. However, NAD+ also serves as a vital co-substrate for a diverse array of enzymes, including sirtuins and PARPs, influencing processes like DNA repair, epigenetic modification, inflammation, and circadian rhythm. Furthermore, recent discoveries highlight its function as a nucleotide analog in DNA ligation and RNA capping. Consequently, dynamic changes in NAD+ levels, driven by cellular stress, significantly rewire biological processes through the post-synthesis modification of DNA, RNA, and proteins, with NAD+ deficiency linked to various diseases, including metabolic disorders, cancer, and neurodegeneration.
Alternative NamesNicotinamide adenine dinucleotide; Coenzyme I; Diphosphopyridine nucleotide (DPN+); β-NAD; β-DPN; 1-(3-Carbamoylpyridinio)-β-D-ribofuranoside 5-(Adenosine-5'-pyrophosphate); Cozymase
Format400 Tests
StorageStore at -20 °C, and protect from light.
HandlingPlease place the product at proper storage condition once received.
ShippingIce bags
Regulatory StatusRUO

For Research Use Only.

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