Pleurocidin, Antimicrobial Peptide (AMP) (CAT#: BMWJ-0826-WJ32)
Pleurocidin is an Antimicrobial peptide. Pleurocidin is derived from the skin mucosa or intestinal secretions of Pseudopleuronectes americanus. Pleurocidin inhibits the expression of key proteins in the MAPK and NF-κB inflammatory signaling pathways. Pleurocidin alters serum inflammatory and immune cytokine levels, regulates the down-regulation of tight junction proteins, and modulates the intestinal flora. Pleurocidin exerts antibacterial activity by inducing bacterial membrane damage, hydroxyl radical formation, and NADH depletion, and also produces a synergistic effect with Antibiotics. Pleurocidin alleviates DSS-induced ulcerative colitis. Pleurocidin can be used for research on ulcerative colitis, bacterial infections, and bacterial biofilm-related infections.
| Overview | |
|---|---|
| Synonyms | Pleurocidin; Pleurocidin peptide |
| Source | Fish |
| CAS | 190324-47-1 |
| Molecular Formula | C129H192N36O29 |
| Molecular Weight | 2711.13 |
| Sequence | Gly-Trp-Gly-Ser-Phe-Phe-Lys-Lys-Ala-Ala-His-Val-Gly-Lys-His-Val-Gly-Lys-Ala-Ala-Leu- Thr-His-Tyr-Leu |
| Sequence Shortening | GWGSFFKKAAHVGKHVGKAALTHYL |
| Activity | Gram-positive bacteria; Gram-negative bacteria; Fungi; Virus; Cancer; Fish |
| Physical State | Powder |
| Purity | >98% |
| Storage | The power can be stored at 4°C for 2 years or at -20°C for 3 years. |
For Research Use Only.
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