Polymyxin B1-D-Leu-d7 TFA, Antimicrobial Peptide (AMP) (CAT#: BMWJ-0826-WJ102)
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Polymyxin B1-D-Leu-d7 TFA is the deuterium labeled Polymyxin B1 (HY-A0248A). Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment.
| Overview | |
|---|---|
| Synonyms | Polymyxin B1-D-Leu-d7 TFA; Polymyxin B1-D-Leu-d7; Polymyxin B1 D-Leu deuterated |
| Source | Bacteria |
| Sequence | {Dab(6-methyl-1-oxooctyl)}-Thr-{Dab}-{Dab}-{Dab}-{d-Phe}-D-Leu-{Dab}-{Dab}-Thr (La ctam bridge: Dab4-Thr10) |
| Sequence Shortening | {Dab(6-methyl-1-oxooctyl)}-T-{Dab}-{Dab}-{Dab}-{d-Phe}-D-{Dab}-{Dab}-T (Lactam bri dge: Dab4-Thr10) |
| Activity | Gram-negative bacteria; LPS; Biofilm; Cationic; Lipopeptide; Outer membrane |
| Physical State | Powder |
| Purity | >98% |
| Storage | The power can be stored at 4°C for 2 years or at -20°C for 3 years. |
For Research Use Only.
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