Retrocyclin-1, Antimicrobial Peptide (AMP) (CAT#: BMWJ-0826-WJ585)
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Retrocyclin-1 is a kind of Theta-defensin. Retrocyclin-1 recognizes and binds to carbohydrate-containing surface molecules, to protect cells from HIV-1 infection. Retrocyclin-1 exhibits high affinity to fetuin, gp120 (Kd=35.4 nM), CD4 (Kd=31 nM), and galactosylceramide (Kd=24.1 nM).
| Overview | |
|---|---|
| Synonyms | Retrocyclin-1; RC-1; θ-defensin analog |
| Source | Not specified |
| Sequence | Cyclo(-Gly-Ile-Cys-Arg-Cys-Ile-Cys-Gly-Arg-Gly-Ile-Cys-Arg-Cys-Ile-Cys-Gly-Arg) (Disulfi de bridge:Cys2-Cys11;Cys4-Cys9;Cys13-Cys18) |
| Sequence Shortening | RCICGRGICRCICGRGIC (Disulfide bridge:Cys2-Cys11;Cys4-Cys9;Cys13-Cys18) |
| Activity | Gram-positive bacteria; Gram-negative bacteria; Fungi; Virus; HIV; Cancer cells; Immunomodulation; LPS |
| Physical State | Powder |
| Purity | >98% |
| Storage | The power can be stored at 4°C for 2 years or at -20°C for 3 years. |
For Research Use Only.
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