Tachyplesin II, Antimicrobial Peptide (AMP) (CAT#: BMWJ-0826-WJ613)
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Tachyplesin II is a broad-spectrum cationic antimicrobial peptide. Tachyplesin II has significant inhibitory effects on Gram-positive bacteria, Gram-negative bacteria, and some fungi. Tachyplesin II binds to bacterial membrane lipopolysaccharides through its positive charge, disrupting membrane integrity and causing leakage of cellular contents. Tachyplesin II can bind to DNA grooves, inhibiting microbial replication, and also suppressing HIV-1 replication and the proliferation of liver cancer cells.
| Overview | |
|---|---|
| Synonyms | Tachyplesin II; Tachyplesin 2; TP-II |
| Source | Marine |
| CAS | 125139-69-7 |
| Molecular Formula | C100H152N34O19S4 |
| Molecular Weight | 2262.8 |
| Sequence | Arg-Trp-Cys-Phe-Arg-Val-Cys-Tyr-Arg-Gly-Ile-Cys-Tyr-Arg-Lys-Cys-Arg (Disulfide bridge :Cys3-Cys16,Cys7-Cys12) |
| Sequence Shortening | RWCFRVCYRGICYRKCR (Disulfide bridge:Cys3-Cys16,Cys7-Cys12) |
| Activity | Gram-positive bacteria; Gram-negative bacteria; Fungi; Virus; Cancer; Biofilm; LPS; Endotoxin; Marine; Horseshoe crab |
| Physical State | Powder |
| Purity | >98% |
| Storage | The power can be stored at 4°C for 2 years or at -20°C for 3 years. |
For Research Use Only.
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