Tachyplesin III, Antimicrobial Peptide (AMP) (CAT#: BMWJ-0826-WJ614)
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Tachyplesin-3 is a broad-spectrum cationic antimicrobial peptide. Tachyplesin-3 has inhibitory activity against Gram-positive bacteria, Gram-negative bacteria, fungi and enveloped viruses. Tachyplesin-3 binds to bacterial membrane lipopolysaccharides through positive charges, disrupting membrane integrity and causing leakage of cellular contents. Tachyplesin-3 interferes with bacterial adhesion and aggregation, prevents biofilm formation, and has a synergistic effect when used in combination with Piperacillin (HY-B1923) - Tazobactam (HY-B1418) (TZP).
| Overview | |
|---|---|
| Synonyms | Tachyplesin-3; Tachyplesin 3; TP-III |
| Source | Marine |
| Sequence | Lys-Trp-Cys-Phe-Arg-Val-Cys-Tyr-Arg-Gly-Ile-Cys-Tyr-Arg-Lys-Cys-Arg-NH2 (Disulfide b ridge:Cys3-Cys16,Cys7-Cys12) |
| Sequence Shortening | KWCFRVCYRGICYRKCR-NH2 (Disulfide bridge:Cys3-Cys16,Cys7-Cys12) |
| Activity | Gram-positive bacteria; Gram-negative bacteria; Fungi; Virus; Cancer; Biofilm; LPS; Endotoxin; Marine; Horseshoe crab |
| Physical State | Powder |
| Purity | >98% |
| Storage | The power can be stored at 4°C for 2 years or at -20°C for 3 years. |
For Research Use Only.
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